Results 81 to 90 of about 248,621 (386)

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source

An intelligent liposome that may deliver drug molecules in a well controlled fashion [PDF]

, 2007
The passage of molecules, especially large ones, through the cellular membrane is a very important problem for some biotechnological applications, such as drug delivery.
Alin Gabriel Popescu, Dumitru Popescu
core   +1 more source

Influence of Micro-mixing on the Size of Liposomes Self-Assembled from Miscible Liquid Phases

, 2013
Ethanol injection and variations of it are a class of methods where two miscible phases---one of which contains dissolved lipids---are mixed together leading to the self-assembly of lipid molecules to form liposomes. This method has been suggested, among
Phapal, Sopan, Sunthar, P
core   +2 more sources

Using small molecules to facilitate exchange of bicarbonate and chloride anions across liposomal membranes [PDF]

, 2009
Bicarbonate is involved in a wide range of biological processes, which include respiration, regulation of intracellular pH and fertilization. In this study we use a combination of NMR spectroscopy and ion-selective electrode techniques to show that the ...
A Fürstner, AP Davis, AV Koulov, C Yamamoto, D Stefayne, E Gout, ED Steinle, F Hofmeister, FA Norris, FG Riddell, HG Hempling, HM Florman, J Fujinaga, Jeffery T. Davis, JL Sessler, Jose Carlos Iglesias-Sánchez, JR Casey, JW Bennett, JY Choi, K Chang, K Kavallieratos, K Tanigaki, L You, M Nguyen, MS Melvin, NM Koropatkin, NN Gerber, NR Williamson, OA Okunola, Oluyomi A. Okunola, Philip A. Gale, Pilar Prados, PV Santacroce, RA Gottlieb, Roberto Quesada, S Ohkuma, T Sato, Tomás Torroba, V Rizzo, WN Lipscomb, WW Cleland, X Li   +41 more
core   +1 more source

Lipid-based nanocarriers to enhance skin permeation and antioxidant activity of Centella asiatica extract [PDF]

MATEC Web of Conferences, 2018
The purpose of this study was to evaluate the use of different formulations, including solution, gel, liposome and niosome for in vitro skin permeation and antioxidant activity of Centella asiatica (CA) extract.
Pamornpathomkul Boonnada, Rangsimawong Worranan, Rojanarata Theerasak, Opanasopit Praneet, Chaiyodsilp Chuleerath, Ngawhirunpat Tanasait   +5 more
doaj   +1 more source

Rotating Liquid Marble Microreactors for Enhanced Enzymatic Reactions

Advanced Functional Materials, EarlyView.
Dynamic magnetic liquid marbles (LMs), stabilized by hydrophobic magnetic proteinaceous colloidosomes, function as effective microreactors for enzymatic processes. Precise magnetic manipulation allows for the rotation of these LMs, enhancing the efficiency of the enzymatic cascade reaction both at the air/water interface and within biphasic enzyme ...
Weijie Jiang, Xin Guan, Wei Liu, Yunxing Li, Hang Jiang, To Ngai   +5 more
wiley   +1 more source

Facilitated engraftment of human hematopoietic cells in severe combined immunodeficient mice following a single injection of Cl²MDP liposomes [PDF]

, 1997
Transplantation of normal and malignant human hematopoietic cells into severe combined immunodeficient (SCID) mice allows for evaluation of long-term growth abilities of these cells and provides a preclinical model for therapeutic interventions. However,
Bos, K van den, Leenen, P.J.M., Loenen, W.A.M., Löwenberg, B., Prins, A., Rooijen, N. van, Terpstra, W., Verstegen, M.M.A., Wagemaker, G., Wielenga, J.J., Wijngaardt, S. van, Wognum, A.W.   +11 more
core   +3 more sources

Biopharmaceutical characterization of topical liposome formulations bearing 5-fluorouracil [PDF]

Makedonsko Farmacevtski Bilten, 2003
Liposome dispersions and liposome gel formulations for topical administration were evaluated as modified release delivery systems for 5-fluorouracil.
Marija Glavas-Dodov, Emilija Fredro-Kumbaradzi, Sema Calis, Katerina Goracinova, Kristina Mladenovska, Maja Simonoska, Atila A. Hincal   +6 more
doaj  

A DNA-Programmed Liposome Fusion Cascade.

Angewandte Chemie, 2017
Chemically engineered and functionalized nanoscale compartments are used in bottom-up synthetic biology to construct compartmentalized chemical processes. Progressively more complex designs demand spatial and temporal control over entrapped species. Here,
P. Löffler, O. Ries, A. Rabe, A. Okholm, Rasmus P. Thomsen, J. Kjems, S. Vogel   +6 more
semanticscholar   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source