Results 11 to 20 of about 255,752 (191)

Enhanced active targeting via cooperative binding of ligands on liposomes to target receptors. [PDF]

open access: yesPLoS ONE, 2013
To achieve effective active targeting in a drug delivery system, we previously developed dual-targeting (DT) liposomes decorated with both vascular endothelial growth factor receptor-1 (VEGFR-1)-targeted APRPG and CD13-targeted GNGRG peptide ligands for ...
Tomoki Sugiyama   +6 more
doaj   +1 more source

Synthesis and Antioxidant Activity of Caffeic Acid Derivatives

open access: yesMolecules, 2018
A series of caffeic acid derivatives were synthesized via a modified Wittig reaction which is a very important tool in organic chemistry for the construction of unsaturated carbon–carbon bonds.
Katarzyna Sidoryk   +4 more
doaj   +1 more source

A pH-sensitive stearoyl-PEG-poly(methacryloyl sulfadimethoxine)-decorated liposome system for protein delivery: an application for bladder cancer treatment [PDF]

open access: yes, 2016
Stealth pH-responsive liposomes for the delivery of therapeutic proteins to the bladder epithelium were prepared using methoxy-poly(ethylene glycol)5kDa-1,2-distearoyl-sn-glycero-3-phosphoethanolamine (mPEG5kDa-DSPE) and stearoyl-poly(ethylene glycol ...
Balasso, Anna   +8 more
core   +1 more source

Technological and theoretical aspects for testing electroporation on liposomes [PDF]

open access: yes, 2017
Recently, the use of nanometer liposomes as nanocarriers in drug delivery systems mediated by nanoelectroporation has been proposed. This technique takes advantage of the possibility of simultaneously electroporating liposomes and cell membrane with 10 ...
Apollonio, Francesca   +5 more
core   +3 more sources

The Vacuolar Pathway in Macrophages Plays a Major Role in Antigen Cross-Presentation Induced by the Pore-Forming Protein Sticholysin II Encapsulated Into Liposomes

open access: yesFrontiers in Immunology, 2018
Cross-presentation is an important mechanism for the differentiation of effector cytotoxic T lymphocytes (CTL) from naïve CD8+ T-cells, a key response for the clearance of intracellular pathogens and tumors.
Yoelys Cruz-Leal   +11 more
doaj   +1 more source

In vitro and in vivo evaluation of liposomes modified with polypeptides and red cell membrane as a novel drug delivery system for myocardium targeting

open access: yesDrug Delivery, 2020
Ischemic cardiac disease (ICD) is a cardiovascular disease with high morbidity and mortality. In this study, a novel myocardial targeted drug delivery system was developed represented by co-modified liposomes consisting of red cell membrane (RCM), and ...
Xueyan Liu   +7 more
doaj   +1 more source

Polymer-Modified Liposomes for Drug Delivery: From Fundamentals to Applications

open access: yesPharmaceutics, 2022
Liposomes are highly advantageous platforms for drug delivery. To improve the colloidal stability and avoid rapid uptake by the mononuclear phagocytic system of conventional liposomes while controlling the release of encapsulated agents, modification of ...
Yifeng Cao, Xinyan Dong, Xuepeng Chen
doaj   +1 more source

Facilitated engraftment of human hematopoietic cells in severe combined immunodeficient mice following a single injection of Cl²MDP liposomes [PDF]

open access: yes, 1997
Transplantation of normal and malignant human hematopoietic cells into severe combined immunodeficient (SCID) mice allows for evaluation of long-term growth abilities of these cells and provides a preclinical model for therapeutic interventions. However,
Bos, K van den   +11 more
core   +3 more sources

Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells [PDF]

open access: yes, 2020
Retinoid treatment is employed during residual disease treatment in neuroblastoma, where the aim is to induce neural differentiation or death in tumour cells.
Bilip, Maja   +11 more
core   +4 more sources

Preparation and Characterization of New Liposomes. Bactericidal Activity of Cefepime Encapsulated into Cationic Liposomes [PDF]

open access: yes, 2019
Cefepime is an antibiotic with a broad spectrum of antimicrobial activity. However, this antibiotic has several side effects and a high degradation rate.
Camacho Sánchez, Vanesa   +6 more
core   +1 more source

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