Susceptibility of Methicillin Resistant Staphylococcus aureus to Vancomycin using Liposomal Drug Delivery System [PDF]
arXiv, 2018 Staphylococcus aureus responsible for nosocomial infections is a significant threat to the public health. The increasing resistance of S.aureus to various antibiotics has drawn it to a prime focus for research on designing an appropriate drug delivery system.
arxiv
Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]
, 2006 During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill +44 more
core +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
OBTAINING AND CHARACTERISTIC OF CURCUMIN LIPOSOMAL FORM [PDF]
Biotechnologia Acta, 2014 Creation of liposomal forms of curcumin (diferuloilmetane) was investegated in the work. The methods of preparation and determination of the obtained liposomes sizes and percentage of curcumin in liposomes are given.
Shulga S. M.
doaj +1 more source
Insertion of a magnesium(II)-octacarboranyl(hexylsulfanyl) porphyrazine into liposomes: a physico-chemical study [PDF]
arXiv, 2007 The synthesis, characterization and liposome insertion of a novel magnesium(II) carboranyl-porphyrazine, i.e. [2,3,7,8,12,13,17,18-octakis- (1,2-dicarba-closo-dodecaboranyl)-hexylthio-5,10,15,20- porphyrazine]magnesium(II) complex, MgHECSPz, is described.
arxiv
Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment [PDF]
, 2020 BACKGROUND: Docetaxel chemotherapy in prostate cancer has a modest impact on survival. To date, efforts to develop combination therapies have not translated into new treatments. We sought to develop a novel therapeutic strategy to tackle chemoresistant
Dufès, Christine +9 more
core +3 more sources
Advanced Functional Materials, EarlyView.Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen +5 more
wiley +1 more source
High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles
Advanced Functional Materials, EarlyView.The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires +4 more
wiley +1 more source
Bladder uptake of liposomes after intravesical administration occurs by endocytosis. [PDF]
PLoS ONE, 2015 Liposomes have been used therapeutically and as a local drug delivery system in the bladder. However, the exact mechanism for the uptake of liposomes by bladder cells is unclear. In the present study, we investigated the role of endocytosis in the uptake
Bharathi Raja Rajaganapathy +4 more
doaj +1 more source
Speckle Tweezers for Simultaneous Controlling of Low and High Refractive Index Micro-particles [PDF]
arXiv, 2021 Manipulation of micro and nanoscale particles suspended in a fluidic medium is one among the defining goals of modern nanotechnology. Speckle tweezers (ST) by incorporating randomly distributed light fields have been used to apply detectable limits on the Brownian motion of micro-particles with refractive indices higher than their medium.
arxiv