Results 81 to 90 of about 338,765 (389)
Advanced Functional Materials, EarlyView.Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen +5 more
wiley +1 more source
Exploring the HYDRAtion method for loading siRNA on liposomes : the interplay between stability and biological activity in human undiluted ascites fluid [PDF]
, 2016 Delivery of small interfering RNA (siRNA) is recently gaining tremendous attention for the treatment of ovarian cancer. The present study investigated the potential of different liposomal formulations composed of (2,3-dioleoyloxy-propyl)trimethylammonium
Braeckmans, Kevin +4 more
core +2 more sources
Spatiotemporal control of coacervate formation within liposomes
Nature Communications, 2019 Liquid-liquid phase separation (LLPS), especially coacervation, plays a crucial role in cell biology, as it forms numerous membraneless organelles in cells.
S. Deshpande +8 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Biopolymers are sustainable, biodegradable alternatives to petroleum‐based plastics for food packaging. Its adoption is often limited by poor mechanical strength, barrier properties, and improved thermal stability through the incorporation of nanofillers.
Himakshi Baishya +2 more
wiley +1 more source
Biomimetic thiamine- and niacin-decorated liposomes for enhanced oral delivery of insulin
Acta Pharmaceutica Sinica B, 2018 Biomimetic nanocarriers are emerging as efficient vehicles to facilitate dietary absorption of biomacromolecules. In this study, two vitamins, thiamine and niacin, are employed to decorate liposomes loaded with insulin, thus facilitating oral absorption ...
Haisheng He +5 more
doaj +1 more source
Development of a DNA-Liposome Complex for Gene Delivery Applications [PDF]
, 2017 The association structures formed by cationic liposomes and DNA(Deoxyribonucleic acid)-liposome have been effectively utilized as gene carriers in transfection assays.
Ambrose, J. J. +9 more
core +1 more source
Native silica nanoparticles are powerful membrane disruptors [PDF]
, 2015 Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I. +3 more
core +1 more source
ACS Nano, 2019 Polyethylene glycol (PEG)-coated nanopharmaceuticals can cause mild-to-severe hypersensitivity reactions (HSRs) which can occasionally be life threatening or even lethal. The phenomenon represents an unsolved immune barrier to the use of these drugs, yet
G. Kozma +11 more
semanticscholar +1 more source
Genetically controlled membrane synthesis in liposomes
Nature Communications, 2020 Lipid membranes, nucleic acids, proteins, and metabolism are essential for modern cellular life. Synthetic systems emulating the fundamental properties of living cells must therefore be built upon these functional elements.
D. Blanken +3 more
semanticscholar +1 more source
High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles
Advanced Functional Materials, EarlyView.The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires +4 more
wiley +1 more source