Results 81 to 90 of about 5,641 (199)
The Scientific World Journal, 2010 The enzymatic oxygenation of polyunsaturated fatty acids by lipoxygenases and cyclo-oxygenases is a resourceful mode of formation of specific autacoids that regulate the extent and pace of the inflammatory response. Arachidonate-derived eicosanoids, such
Gerard L. Bannenberg
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Arachidonic acid in health and disease with focus on hypertension and diabetes mellitus: A review
Journal of Advanced Research, 2018 Arachidonic acid (AA 20:4n-6) is an essential component of cell membranes and modulates cell membrane fluidity. AA is metabolized by cyclo-oxygenase (COX), lipoxygenase (LOX) and cytochrome P450 enzymes to form several metabolites that have important ...
Undurti N. Das
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Aging Cell, Volume 25, Issue 5, May 2026.We provide the first human evidence that the exercise‐induced myokine irisin mediates the relationship between physical activity and hippocampal volume in older adults, with strongest effects in CA1, CA3 and CA4 subfields. These regions are critical for memory and particularly vulnerable to Alzheimer's disease.
Thomas Pace +5 more
wiley +1 more source
Effect of lipoxin A4 on IMR-32 cells.
, 2014 IMR-32 cells were exposed to different doses (1, 5, 10 ng/ml) of lipoxin A4 and incubated for 24 hrs. At the end of treatment period, cell viability was measured by MTT assay.
Arul M. Mani (678608) +5 more
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 9, Page 2049-2060, May 2026.Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma +9 more
wiley +1 more source
Lipoxin A4 receptor dependent leishmania infection
Autoimmunity, 2009 The lipoxin A4 receptor (ALX) is an important target of LxA4 in synovial tissues of patients with inflammatory arthritis. Previously this receptor was known as the FPRL-1 on PMN and shown to interact with acute phase proteins and a variety of peptides. ALX signalling can either activate or deactivate PMN functions.
Alexander Wenzel, Ger Van Zandbergen
openaire +3 more sources
Frontiers in Microbiology, 2019 Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, particularly latent infection is often associated with inflammation. The arachidonic acid pathway, the home of several inflammation and resolution associated lipid mediators, is widely altered ...
Jayashree A. Chandrasekharan +1 more
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Food Science &Nutrition, Volume 14, Issue 4, April 2026.This study investigated whether Lacticaseibacillus paracasei Zhang could alleviate the gut microbiota imbalance and its systemic consequences caused by antibiotics. Mice treated with azithromycin exhibited gut microbiota disorders, and subsequent probiotic intervention was carried out.
Xiaoye Liu +4 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 4, April 2026.JDK and kaempferol upregulate ANXA1 in oral epithelia, which bind to fibroblast FPR2 to suppress myofibroblast activation, and collagen deposition, while reducing neutrophil recruitment and inflammation, thereby restoring epithelial‐fibroblast homeostasis to alleviate arecoline‐induced OSF. ABSTRACT Oral submucous fibrosis (OSF) is a betel quid chewing‐
Yao Xiao +6 more
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Frontiers in Cardiovascular Medicine, 2019 Background: Inflammation and hypercoagulability play a pivotal role in venous thromboembolism and atherothrombosis. Since venous thrombosis increases the risk of atherothrombotic events and vice versa, common mechanisms may be involved.Objectives: To ...
Bram M. M. Kremers +14 more
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