Results 61 to 70 of about 93,050 (197)

Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells.

PLoS ONE, 2023
Airway diseases can disrupt tight junction proteins, compromising the epithelial barrier and making it more permeable to pathogens. In people with pulmonary disease who are prone to infection with Pseudomonas aeruginosa, pro-inflammatory leukotrienes are
Kameljit K Kalsi, Sonya Jackson, Deborah L Baines   +2 more
doaj   +1 more source

In Vitro Anti‐Inflammatory Activity of Sour Cherry (Prunus cerasus L.) Seed Oil and Computational Safety Profiling

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
In vitro anti‐inflammatory activity of sour cherry (Prunus cerasus L.) seed oil and computational safety profiling. ABSTRACT This study aimed to evaluate the in vitro anti‐inflammatory activity of sour cherry seed oils, including samples obtained by Soxhlet extraction and maceration, as well as ten commercial samples.
Tuğba Aydin, Tuğba Günbatan, Aysel Berkkan, Onur Kenan Ulutaş, Melike Sucu   +4 more
wiley   +1 more source

15-epi-lipoxin A4 reduces the mortality of prematurely born pups in a mouse model of infection-induced preterm birth [PDF]

, 2015
Preterm birth remains the leading cause of neonatal mortality and morbidity worldwide. There are currently few effective therapies and therefore an urgent need for novel treatments.
R. D. Catalano, Rossi, A. G., Rossi, A G, Wade, J., A. G. Rossi, Catalano, R D, Wade, J, Rinaldi, S. F., Rinaldi, S F, Norman, J. E., Catalano, R. D., S. F. Rinaldi, J. Wade, J. E. Norman, Norman, J E   +14 more
core   +1 more source

Glucocorticoid Exposure Induces Preeclampsia via DampeningLipoxin A4, an Endogenous Anti-Inflammatory and Proresolving Mediator

Frontiers in Pharmacology, 2020
The pathogenesis of preeclampsia (PE) involves several pathophysiological processes that may be affected by glucocorticoid (GC). We confirmed previously that GC exposure could result in PE, while PE is linked to a deficiency of lipoxin A4 (LXA4), an ...
Haojing Liu, Wei Huang, Liping Chen, Qiang Xu, Duyun Ye, Dongxin Zhang   +5 more
doaj   +1 more source

Complement Activation by Post‐Translationally Modified Proteins: Links to Chronic Inflammation and Autoimmunity

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
Marleen M. J. van Greevenbroek, Leendert A. Trouw   +1 more
wiley   +1 more source

Lipoxin A4 Activates Alveolar Epithelial Sodium Channel, Na,K-ATPase, and Increases Alveolar Fluid Clearance

, 2013
Edema fluid resorption is critical for gas exchange, and both alveolar epithelial sodium channel (ENaC) and Na,K-ATPase are accredited with key roles in the resolution of pulmonary edema.
Ying, Bin-Yu, Ru Li, Wu, De-Rong, Zheng, Xia, Jin, Sheng-Wei, Bin-Yu Ying, Chang-Jiang Huang, He, Qian, Huang, Chang-Jiang, Qian Wang, Fang Chen, De-Rong Wu, Sheng-Xing Zheng, Zheng, Sheng-Xing, Qing-Quan Lian, Lian, Qing-Quan, Smith, Fang Gao; id_orcid, Chen, Fang, Yi Yang, Qian He, Li, Ru, Wang, Qian, Sheng-Wei Jin, Xia Zheng, Fang Gao Smith, Yang, Yi   +25 more
core   +1 more source

The Role of Immunoresolvents in Atherosclerosis: A Mini‐Review on Their Biology and Therapeutic Opportunities

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Ramin Lotfi, Alireza Nasirifar, Hoda Rahmani, Sara Falahi, Meysam Kashiri   +4 more
wiley   +1 more source

Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner [PDF]

Oxidative Medicine and Cellular Longevity, 2016
Oxidative stress plays a critical role in the pathogenesis of intestinal ischemia reperfusion (IIR) injury. Enhancement in endogenous Lipoxin A4 (LXA4), a potent antioxidant and mediator, is associated with attenuation of IIR. However, the effects of LXA4 on IIR injury and the potential mechanisms are unknown.
Hei, Z, Zhang, Z, Li, H, LIU, Z, Yao, W, Han, X, Xia, Z   +6 more
openaire   +4 more sources

Regional arterial infusion with lipoxin A4 attenuates experimental severe acute pancreatitis [PDF]

, 2014
Objective: Investigate the therapeutic effect of regional arterial infusion (RAI) with Aspirin-Triggered Lipoxin A4 (ATL) in experimental severe acute pancreatitis (SAP) in ...
Andersson, Roland, Bicheng Chen, Andersson, Roland,, Jin, Yuepeng, Xu, Dan, Yangyun Xie, Xie, Yangyun,, Yang, Fajing, Xie, Jianming, Jianming Xie, Xie, Jianming,, Roland Andersson, Yang, Fajing,, Zhou, Mengtao, Chen, Bicheng,, Chen, Bicheng, Sun, Hongwei, Fajing Yang, Xie, Yangyun, Hongwei Sun, Weiming Wang, Sun, Hongwei,, Zhou, Mengtao,, Xu, Dan,, Wang, Weiming,, Wang, Weiming, Jin, Yuepeng,, Lund University., Yuepeng Jin, Dan Xu, Mengtao Zhou   +30 more
core   +2 more sources

Intervertebral disc degeneration, inflammation, and bioactive lipids

Recent Trends in Pharmacology
Intervertebral disc degeneration, inflammation, and bioactive lipidsIntervertebral disc degenerationIntervertebral disc (IVD) degeneration is a common condition that is associated with significant morbidity.
Undurti Das, Ahmet Hacımüftüoğlu
doaj   +1 more source