Results 41 to 50 of about 5,641 (199)

Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice.

PLoS ONE, 2014
When 5-lipoxygenase (5-LO) is inhibited, roughly half of the CNS effect of the prototypic endocannabinoid anandamide (AEA) is lost. Therefore, we decided to investigate whether inhibiting this enzyme would influence physiological functions classically ...
Luciana M Leo, Suellen Almeida-Corrêa, Claudio A Canetti, Olavo B Amaral, Fernando A Bozza, Fabricio A Pamplona   +5 more
doaj   +1 more source

Inflammation and pro-resolution inflammation after hepatobiliary surgery

World Journal of Surgical Oncology, 2017
Background The magnitude of the perioperative inflammatory response plays a role in surgical outcomes. However, few studies have explored the mechanisms of the resolution of inflammation in the context of surgery. Here, we described the temporal kinetics
Juan P. Cata, Jose F. Velasquez, Maria F. Ramirez, Jean-Nicolas Vauthey, Vijaya Gottumukkala, Claudius Conrad, Bradford J. Kim, Thomas Aloia   +7 more
doaj   +1 more source

Gamma-Linolenic Acid (GLA) Protects against Ionizing Radiation-Induced Damage: An In Vitro and In Vivo Study

Biomolecules, 2022
Radiation is pro-inflammatory in nature in view of its ability to induce the generation of reactive oxygen species (ROS), cytokines, chemokines, and growth factors with associated inflammatory cells. Cells are efficient in repairing radiation-induced DNA
Poorani Rengachar, Anant Narayan Bhatt, Sailaja Polavarapu, Senthil Veeramani, Anand Krishnan, Monika Sadananda, Undurti N. Das   +6 more
doaj   +1 more source

Up-Regulation of Annexin-A1 and Lipoxin A(4) in Individuals with Ulcerative Colitis May Promote Mucosal Homeostasis

, 2012
PubMed ID: 22723974This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Jose G P Ferraz, Linda Vong, Panaccione, R, Panaccione Remo, Philip M. Sherman, Philip M Sherman, Perretti, M, Beck Paul L., Ferraz, JGP, Sherman Philip M., John L. Wallace, Vong Linda, Sherman, PM, Wallace John L., Mauro Perretti, Jose G. P. Ferraz, Paul L. Beck, Neil Dufton, Remo Panaccione, Dufton, N, Ferraz Jose G. P., Beck, PL, Dufton Neil, Wallace, JL, Vong, L, John L Wallace, Perretti Mauro, Paul L Beck   +27 more
core   +1 more source

Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome [PDF]

, 2021
The chronic neuro-inflammatory character of multiple sclerosis (MS) suggests that the natural process to resolve inflammation is impaired. This protective process is orchestrated by specialized pro-resolving lipid mediators (SPMs), but to date, the role ...
Silvia Martina Tietz, Alessandro Leuti, Valerio Chiurchiu, Serhan, Charles N, Tietz, Silvia Martina, Haghayegh Jahromi, Neda, Norris, Paul C, Schouten, Marijn, de Vries, Helga E., Neda Haghayegh Jahromi, Helga de Vries, Enzmann, Gaby, Charles N Serhan, Jahromi, Neda Haghayegh, Chiurchiù, Valerio, Gaby Enzmann, Kooij, Gijs, van der Pol, Susanne M. A., Engelhardt, Britta, van der Pol, Susanne M A, Britta Engelhardt, Norris, Paul C., Serhan, Charles N., Claudio Derata Troletti, Kamermans, Alwin, Leuti, Alessandro, Paul C Norris, de Vries, Helga E, Alwin Kamermans, Derada Troletti, Claudio, Gijs Kooij, Susanne M.A. van der Pol, Marijn Schouten,   +32 more
core   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines

Journal of Neuroinflammation, 2012
Background The neuroinflammatory responses in the spinal cord following bone cancer development have been shown to play an important role in cancer-induced bone pain (CIBP).
Hu Shan, Mao-Ying Qi-Liang, Wang Jun, Wang Zhi-Fu, Mi Wen-Li, Wang Xiao-Wei, Jiang Jian-Wei, Huang Ya-Lin, Wu Gen-Cheng, Wang Yan-Qing   +9 more
doaj   +1 more source

Localized Periodontitis in Young Individuals: Aggregatibacter JP2 Clone, Immunological Dysfunctions and Other Stories

Journal of Periodontal Research, EarlyView.
This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali, Meaad M. Alamri, Manuela Maria Viana Miguel, Luciana Shaddox   +3 more
wiley   +1 more source

Papel dual da lipoxina A4, nas alterações inflamatórias e cardiovasculares na sepse: uma janela de oportunidade [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A pneumonia é uma das principais causas de sepse, que por sua vez é a maior causa de morte nas ...
Sordi, Regina de
core  

Lipoxin A4 Activates Alveolar Epithelial Sodium Channel, Na,K-ATPase, and Increases Alveolar Fluid Clearance

, 2013
Edema fluid resorption is critical for gas exchange, and both alveolar epithelial sodium channel (ENaC) and Na,K-ATPase are accredited with key roles in the resolution of pulmonary edema.
Ying, Bin-Yu, Ru Li, Wu, De-Rong, Zheng, Xia, Jin, Sheng-Wei, Bin-Yu Ying, Chang-Jiang Huang, He, Qian, Huang, Chang-Jiang, Qian Wang, Fang Chen, De-Rong Wu, Sheng-Xing Zheng, Zheng, Sheng-Xing, Qing-Quan Lian, Lian, Qing-Quan, Smith, Fang Gao; id_orcid, Chen, Fang, Yi Yang, Qian He, Li, Ru, Wang, Qian, Sheng-Wei Jin, Xia Zheng, Fang Gao Smith, Yang, Yi   +25 more
core   +1 more source