Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. [PDF]
PLoS ONE, 2014 The critical fatty acids Docosahexaenoic Acid (DHA) and Arachidonic Acid (AA) decline in preterm infants within the first postnatal week and are associated with neonatal morbidities, including bronchopulmonary dysplasia (BPD).
Camilia R Martin +7 more
doaj +2 more sources
Lipoxin A4 and Resolvin D1 Preserve Neural Inductive Capacity of Dental Pulp Stem Cells Cultured Under Inflammatory Conditions. [PDF]
Cell Biol IntABSTRACT Human dental pulp stem cells (DPSCs) exhibit neurogenic differentiation potential; however, inflammatory conditions may impair this process. This study investigated the impact of tumor necrosis factor alpha (TNF‐α) on the neurodifferentiation potential of DPSCs and the modulatory role of the pro‐resolving lipid mediators lipoxin A4 (LXA4) and ...
Turrioni AP +6 more
europepmc +2 more sources
Mediators of Inflammation, 2019 Our previous studies verified the potent anti-inflammatory effects against severe acute pancreatitis (SAP) of AT-Lipoxin A4 and their analogues. However, the anti-inflammatory effects of AT-Lipoxin A4 on SAP-associated lung injury are not thoroughly ...
Suhui Yu +7 more
doaj +2 more sources
Neural Regeneration Research, 2016 Lipoxin A4 can alleviate cerebral ischemia/reperfusion injury by reducing the inflammatory reaction, but it is currently unclear whether it has a protective effect on diabetes mellitus complicated by focal cerebral ischemia/reperfusion injury.
Jiang-quan Han +5 more
doaj +2 more sources
Natural Compounds Such as Hericium erinaceus and Coriolus versicolor Modulate Neuroinflammation, Oxidative Stress and Lipoxin A4 Expression in Rotenone-Induced Parkinson’s Disease in Mice [PDF]
Biomedicines, 2022 Background: A growing body of research suggests that oxidative stress and neuroinflammation are early pathogenic features of neurodegenerative disorders. In recent years, the vitagene system has emerged as a potential target, as it has been shown to have
Marika Cordaro +14 more
doaj +2 more sources
Lipoxin A4 promotes lung epithelial repair whilst inhibiting fibroblast proliferation [PDF]
ERJ Open Research, 2016 Therapy that promotes epithelial repair whilst protecting against fibroproliferation is critical for restoring lung function in acute and chronic respiratory diseases.
Shengxing Zheng +10 more
doaj +2 more sources
Lipoxin and Aspirin-Triggered Lipoxins
Scientific World Journal, The, 2010 Lipoxins and their 15 epimers, aspirin triggered lipoxins (ATL), are eicosanoids derived from sequential lipoxygenase (LO) metabolism of arachidonic acid.
Mario Romano
exaly +2 more sources
Association between arachidonate lipoxygenase 15,c.-292 C > T gene polymorphism and non-cystic fibrosis bronchiectasis in children: a pilot study on the effects on airway lipoxin A4 and disease phenotype [PDF]
Italian Journal of PediatricsBackground Persistent airway inflammation is a central feature of bronchiectasis. Arachidonate 15-lipoxygenase (ALOX-15) controls production of endogenous lipid mediators, including lipoxins that regulate airway inflammation.
Mahitab Morsy Hussein +5 more
doaj +2 more sources
Lipoxin A4 (LXA4) for diabetic retinopathy (DR) [PDF]
Indian Journal of OphthalmologyUndurti N Das
doaj +2 more sources
Plasma lipoxin A4 levels in childhood chronic spontaneous urticaria [PDF]
The Turkish Journal of Pediatrics, 2018 Chronic spontaneous urticaria (CSU) is an idiopathic inflammatory disorder. Despite great research progress, the pathogenesis of the disease is still not fully understood.
Fatih Dilek +7 more
doaj +5 more sources