Results 11 to 20 of about 5,641 (199)
THE ROLE OF LIPOXIN A4 IN CYSTIC FIBROSIS LUNG DISEASE
Computational and Structural Biotechnology Journal, 2013 In Cystic Fibrosis (CF), mutations of the CFTR gene result in defective Cl− secretion and Na+ hyperabsorption by epithelia which leads to airway lumen dehydration and mucus plugging and favours chronic bacterial colonization, persistent inflammation and ...
Valérie Urbach +3 more
doaj +4 more sources
Study Of Role Of Lipoxin – A4 In Psoriasis [PDF]
Egyptian Journal of Medical Research, 2022 The aim of this work was to evaluate the level of lipoxin – A4 (LXA4) in patients with psoriasis and its correlation with clinical parameters. This study included 25 psoriatic patients who were recruited from the outpatient clinics of dermatology ...
Hanan Al Nemr +3 more
doaj +2 more sources
Mediators of Inflammation, 2013 The lipoxins are the first proresolution mediators to be recognized and described as the endogenous “braking signals” for inflammation. We evaluated the anti-inflammatory and proresolution bioactions of lipoxin A4 in our lipopolysaccharide (LPS-)induced ...
Yi Yang +10 more
doaj +2 more sources
Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. [PDF]
PLoS ONE, 2014 The critical fatty acids Docosahexaenoic Acid (DHA) and Arachidonic Acid (AA) decline in preterm infants within the first postnatal week and are associated with neonatal morbidities, including bronchopulmonary dysplasia (BPD).
Camilia R Martin +7 more
doaj +2 more sources
Mediators of Inflammation, 2019 Our previous studies verified the potent anti-inflammatory effects against severe acute pancreatitis (SAP) of AT-Lipoxin A4 and their analogues. However, the anti-inflammatory effects of AT-Lipoxin A4 on SAP-associated lung injury are not thoroughly ...
Suhui Yu +7 more
doaj +2 more sources
Neural Regeneration Research, 2016 Lipoxin A4 can alleviate cerebral ischemia/reperfusion injury by reducing the inflammatory reaction, but it is currently unclear whether it has a protective effect on diabetes mellitus complicated by focal cerebral ischemia/reperfusion injury.
Jiang-quan Han +5 more
doaj +2 more sources
Airway Lipoxin A4 Generation and Lipoxin A4 Receptor Expression Are Decreased in Severe Asthma [PDF]
American Journal of Respiratory and Critical Care Medicine, 2008 Abstract Rationale Airway inflammation is common in severe asthma despite antiinflammatory therapy with corticosteroids. Lipoxin A4 (LXA4) is an arachidonic acid–derived mediator that serves as an agonist for resolution of inflammation ...
Planaguma, Anna +16 more
openaire +5 more sources
Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A4 [PDF]
Mediators of Inflammation, 2016 We investigated the effects of Crotoxin (CTX), the main toxin of South American rattlesnake (Crotalus durissus terrificus) venom, on Walker 256 tumor growth, the pain symptoms associated (hyperalgesia and allodynia), and participation of endogenous ...
Patrícia Brigatte +7 more
doaj +2 more sources
Plasma lipoxin A4 levels in childhood chronic spontaneous urticaria [PDF]
The Turkish Journal of Pediatrics, 2018 Chronic spontaneous urticaria (CSU) is an idiopathic inflammatory disorder. Despite great research progress, the pathogenesis of the disease is still not fully understood.
Fatih Dilek +7 more
doaj +5 more sources
Effect of Lipoxin A4 on Lipopolysaccharide-Induced Endothelial Hyperpermeability [PDF]
The Scientific World Journal, 2011 Excessive oxidative stress, decreased antioxidant capacity, and enhanced cellular calcium levels are initial factors that cause endothelial cell (EC) hyperpermeability, which represents a crucial event in the pathogenesis of pre-eclampsia.
Huayan Pang +9 more
doaj +2 more sources