Results 51 to 60 of about 5,641 (199)

15-epi-lipoxin A4 reduces the mortality of prematurely born pups in a mouse model of infection-induced preterm birth [PDF]

, 2015
Preterm birth remains the leading cause of neonatal mortality and morbidity worldwide. There are currently few effective therapies and therefore an urgent need for novel treatments.
R. D. Catalano, Rossi, A. G., Rossi, A G, Wade, J., A. G. Rossi, Catalano, R D, Wade, J, Rinaldi, S. F., Rinaldi, S F, Norman, J. E., Catalano, R. D., S. F. Rinaldi, J. Wade, J. E. Norman, Norman, J E   +14 more
core   +1 more source

Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils. [PDF]

Journal of Biological Chemistry, 1992
Lipoxin A4 stimulates rapid lipid remodeling and a pertussis toxin-sensitive release of arachidonic acid in polymorphonuclear leukocytes (PMN) (Nigam, S., Fiore, S., Luscinskas, F.W., and Serhan, C.N. (1990) J. Cell. Physiol. 143, 512-523) and has been shown to inhibit leukocyte responses in several systems.
S, Fiore, S W, Ryeom, P F, Weller, C N, Serhan   +3 more
openaire   +6 more sources

Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?

Medicina, 2020
It is proposed that the bioactive lipid, arachidonic acid (AA, 20:4 n-6), can inactivate severe acute respiratory syndrome(SARS-CoV-2), facilitate M1 and M2 macrophage generation, suppress inflammation, prevent vascular endothelial cell damage, and ...
Undurti N. Das
doaj   +1 more source

Periodontitis as a Model for Inflammatory Uncoupling of Bone Remodeling

Journal of Periodontal Research, EarlyView.
Periodontitis can be viewed as a state of inflammatory uncoupling of bone remodeling, in which excessive osteoclast‐mediated resorption coexists with impaired bone formation. This review integrates emerging insights from osteoimmunology, osteocyte biology, mechanobiology, aging, and resolution pathways to position periodontitis as an accessible in vivo
Rafael Scaf de Molon, Sotirios Tetradis, Rolando Vernal, Fabio Renato Manzolli Leite, Thomas E. Van Dyke   +4 more
wiley   +1 more source

Lipoxina A4 na dor neuropática após a lesão medular: modulação da neuroinflamação e ativação microglial [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2015.A dor crônica está presente na maioria dos pacientes após a lesão medular traumática (LMT).
Martini, Alessandra Cadete
core  

Regional arterial infusion with lipoxin A4 attenuates experimental severe acute pancreatitis [PDF]

, 2014
Objective: Investigate the therapeutic effect of regional arterial infusion (RAI) with Aspirin-Triggered Lipoxin A4 (ATL) in experimental severe acute pancreatitis (SAP) in ...
Andersson, Roland, Bicheng Chen, Andersson, Roland,, Jin, Yuepeng, Xu, Dan, Yangyun Xie, Xie, Yangyun,, Yang, Fajing, Xie, Jianming, Jianming Xie, Xie, Jianming,, Roland Andersson, Yang, Fajing,, Zhou, Mengtao, Chen, Bicheng,, Chen, Bicheng, Sun, Hongwei, Fajing Yang, Xie, Yangyun, Hongwei Sun, Weiming Wang, Sun, Hongwei,, Zhou, Mengtao,, Xu, Dan,, Wang, Weiming,, Wang, Weiming, Jin, Yuepeng,, Lund University., Yuepeng Jin, Dan Xu, Mengtao Zhou   +30 more
core   +1 more source

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

Periodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source

Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner [PDF]

Oxidative Medicine and Cellular Longevity, 2016
Oxidative stress plays a critical role in the pathogenesis of intestinal ischemia reperfusion (IIR) injury. Enhancement in endogenous Lipoxin A4 (LXA4), a potent antioxidant and mediator, is associated with attenuation of IIR. However, the effects of LXA4 on IIR injury and the potential mechanisms are unknown.
Hei, Z, Zhang, Z, Li, H, LIU, Z, Yao, W, Han, X, Xia, Z   +6 more
openaire   +4 more sources

Lipoxin A4 Regulates Natural Killer Cell and Type 2 Innate Lymphoid Cell Activation in Asthma

, 2022
Asthma is a prevalent disease of chronic inflammation in which endogenous counter-regulatory signaling pathways are dysregulated. Recent evidence suggests that innate lymphoid cells (ILCs), including natural killer (NK) cells and type 2 innate lymphoid ...
Barnig, Cindy, Perrella, Mark, Dutile, Stefanie, Israel, Elliot, Kazani, Shamsah, Levy, Bruce, Cernadas, Manuela, Liu, Xiaoli, Wechsler, Michael E.   +8 more
core   +1 more source

A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae

Nature Communications, 2015
Exposure of Anopheles gambiae mosquitoes to Plasmodium infection enhances the ability of their immune system to respond to subsequent infections. However, the molecular mechanism that allows the insect innate immune system to ‘remember’ a previous ...
Jose Luis Ramirez, Giselle de Almeida Oliveira, Eric Calvo, Jesmond Dalli, Romain A. Colas, Charles N. Serhan, Jose M. Ribeiro, Carolina Barillas-Mury   +7 more
doaj   +1 more source