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Highlighting the Effect of Pro-inflammatory Mediators in the Pathogenesis of Periodontal Diseases and Alzheimer's Disease.

open access: yesJ Pharm Bioallied Sci
Hashim N   +5 more
europepmc   +1 more source
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Lipoxins in inflammation

Clinical Hemorheology and Microcirculation, 2022
Lipoxins and ATL appear to be the first recognized members of a new class of endogenous mediator that are anti-inflammatory or serve for the “pro-resolution” of inflammation. PGE2 can and may display anti-inflammatory properties in certain settings, but in most cases, it enhances inflammation in vivo.
Shivani, Sachdeva   +4 more
openaire   +2 more sources

Lipoxins and lipoxin analogs in asthma

Prostaglandins, Leukotrienes and Essential Fatty Acids, 2005
The pathobiology of asthma is characterized by production of eicosanoids, a diverse family of bioactive fatty acids that play important roles in regulating airway inflammation and reactivity. Lipoxins (LXs) are products of arachidonic acid metabolism that are distinct from leukotrienes (LTs) and prostaglandins (PGs) in structure and function.
openaire   +2 more sources

Lipoxins and aspirin-triggered lipoxins in resolution of inflammation

European Journal of Pharmacology, 2015
The resolution of the inflammatory response is highly regulated by the timely biosynthesis of a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers, aspirin triggered lipoxins (ATL) derived by the lipoxygenase (LO) route of arachidonic acid metabolism. In particular, they are formed and released by cells expressing 5-,
ROMANO, Mario   +3 more
openaire   +3 more sources

Lipoxin analogs and lipoxin formation in vivo

Prostaglandins, Leukotrienes and Essential Fatty Acids, 2005
The definition of lipoxin bioactions in vivo and of lipoxin levels in humans, under physiological and pathological conditions, represents a main task toward the clinical use of lipoxins. The introduction of lipoxin stable analogs and of new methodology for immunological measurements of lipoxin A4 in human fluids is significantly contributing to fulfill
openaire   +3 more sources

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