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Lipoxin A4 pretreatment mitigates skeletal muscle ischemia-reperfusion injury in rats.
Hui Zong +4 more
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Host Modulation in Periodontology: Redefining Therapy Beyond Scaling and Root Planing. [PDF]
Dewanjee P +4 more
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Clinical Hemorheology and Microcirculation, 2022
Lipoxins and ATL appear to be the first recognized members of a new class of endogenous mediator that are anti-inflammatory or serve for the “pro-resolution” of inflammation. PGE2 can and may display anti-inflammatory properties in certain settings, but in most cases, it enhances inflammation in vivo.
Shivani, Sachdeva +4 more
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Lipoxins and ATL appear to be the first recognized members of a new class of endogenous mediator that are anti-inflammatory or serve for the “pro-resolution” of inflammation. PGE2 can and may display anti-inflammatory properties in certain settings, but in most cases, it enhances inflammation in vivo.
Shivani, Sachdeva +4 more
openaire +2 more sources
Lipoxins and lipoxin analogs in asthma
Prostaglandins, Leukotrienes and Essential Fatty Acids, 2005The pathobiology of asthma is characterized by production of eicosanoids, a diverse family of bioactive fatty acids that play important roles in regulating airway inflammation and reactivity. Lipoxins (LXs) are products of arachidonic acid metabolism that are distinct from leukotrienes (LTs) and prostaglandins (PGs) in structure and function.
openaire +2 more sources
Lipoxins and aspirin-triggered lipoxins in resolution of inflammation
European Journal of Pharmacology, 2015The resolution of the inflammatory response is highly regulated by the timely biosynthesis of a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers, aspirin triggered lipoxins (ATL) derived by the lipoxygenase (LO) route of arachidonic acid metabolism. In particular, they are formed and released by cells expressing 5-,
ROMANO, Mario +3 more
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Lipoxin analogs and lipoxin formation in vivo
Prostaglandins, Leukotrienes and Essential Fatty Acids, 2005The definition of lipoxin bioactions in vivo and of lipoxin levels in humans, under physiological and pathological conditions, represents a main task toward the clinical use of lipoxins. The introduction of lipoxin stable analogs and of new methodology for immunological measurements of lipoxin A4 in human fluids is significantly contributing to fulfill
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