Results 1 to 10 of about 368 (112)

Lipoxin and Aspirin-Triggered Lipoxins [PDF]

Scientific World Journal, The, 2010
Lipoxins and their 15 epimers, aspirin triggered lipoxins (ATL), are eicosanoids derived from sequential lipoxygenase (LO) metabolism of arachidonic acid.
Mario Romano, Romano Mario
exaly   +5 more sources

Lipoxin Receptors [PDF]

Scientific World Journal, The, 2007
Lipoxins (LXs) represent a class of arachidonic acid (AA) metabolites that carry potent immunoregulatory and anti-inflammatory properties, LXA4 and LXB4 being the main components of this series. LXs are generated by cooperation between 5-lipoxygenase (LO)
Mario Romano, Antonio Recchiuti, Recchiuti Antonio   +2 more
exaly   +6 more sources

Lipoxins as Modulators of Diseases

Cells
Lipoxins were discovered 40 years ago, and since then, their beneficial roles for human health have been confirmed in numerous studies. These small molecules belong to the eicosanoid class of compounds, which are generated metabolically by lipoxygenases.
Uzma Saqib, Monika Pandey, Anjali Vyas, Preeti Patidar, Sumati Hajela, Asgar Ali, Meenakshi Tiwari, Sutripta Sarkar, Neelam Yadav, Shivani Patel, Deepali Shukla, Grace N. Lienemann, Fletcher A. White, Herney Andrés García-Perdomo, Mirza Saqib Baig, Ganesh V. Halade, Krishnan Hajela, Sadhana Sharma, Alexander G. Obukhov   +18 more
doaj   +3 more sources

Lipoxin A4 attenuates the lung ischaemia reperfusion injury in rats after lung transplantation

Annals of Medicine, 2021
Background Lung ischaemia reperfusion injury (LIRI) is the major cause of primary lung dysfunction after lung transplantation. Lipoxin A4 inhibits the oxidative stress and inflammation.
Lijuan Zhang, Qihang Tai, Guangxiao Xu, Wei Gao   +3 more
doaj   +1 more source

Resolution of Inflammation after Skeletal Muscle Ischemia–Reperfusion Injury: A Focus on the Lipid Mediators Lipoxins, Resolvins, Protectins and Maresins

Antioxidants, 2022
Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via systemic effects related to inflammation and oxidative stress.
Cindy Barnig, Gaetan Lutzweiler, Margherita Giannini, Anne Lejay, Anne-Laure Charles, Alain Meyer, Bernard Geny   +6 more
doaj   +1 more source

Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. [PDF]

PLoS ONE, 2014
The critical fatty acids Docosahexaenoic Acid (DHA) and Arachidonic Acid (AA) decline in preterm infants within the first postnatal week and are associated with neonatal morbidities, including bronchopulmonary dysplasia (BPD).
Camilia R Martin, Munir M Zaman, Calvin Gilkey, Maria V Salguero, Hatice Hasturk, Alpdogan Kantarci, Thomas E Van Dyke, Steven D Freedman   +7 more
doaj   +1 more source

Lipoxins and Resolvins in Patients With Pancreatic Cancer: A Preliminary Report

Frontiers in Oncology, 2022
Eicosanoids are bioactive lipids derived from arachidonic acid, which have emerged as key regulators of a wide variety of pathophysiological processes in recent times and are implicated as mediators of gastrointestinal cancer.
Wojciech Blogowski, Katarzyna Dolegowska, Anna Deskur, Barbara Dolegowska, Teresa Starzynska   +4 more
doaj   +1 more source

Lipoxin A4 and platelet activating factor are involved in E. coli or LPS-induced lung inflammation in CFTR-deficient mice. [PDF]

PLoS ONE, 2014
CFTR (cystic fibrosis transmembrane conductance regulator) is expressed by both neutrophils and platelets. Lack of functional CFTR could lead to severe lung infection and inflammation.
Haiya Wu, Jun Yang, Emily M Su, Ling Li, Caiqi Zhao, Xi Yang, Zhaowei Gao, Mengyao Pan, Peiyu Sun, Wei Sun, Yiyi Jiang, Xiao Su   +11 more
doaj   +1 more source

Resolution-Based Therapies: The Potential of Lipoxins to Treat Human Diseases

Frontiers in Immunology, 2021
Inflammation is an a physiological response instead an essential response of the organism to injury and its adequate resolution is essential to restore homeostasis.
Rafael I. Jaén, Rafael I. Jaén, Sergio Sánchez-García, María Fernández-Velasco, María Fernández-Velasco, Lisardo Boscá, Lisardo Boscá, Patricia Prieto, Patricia Prieto, Patricia Prieto   +9 more
doaj   +1 more source

Lipoxins: regulators of resolution [PDF]

Current Opinion in Pharmacology, 2010
Persistent inflammation underlies many prevalent diseases including atherosclerosis and diabetes. There is a growing appreciation that inflammation and its active resolution may be modulated by endogenously produced lipids. Pre-eminent amongst these mediators are lipoxin [LX]A4 and LXB4.
Ryan, Aidan, Godson, Catherine
openaire   +4 more sources