Results 11 to 20 of about 52,843 (179)

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Effect of Temperature on Lipoxygenase Activity in Varieties of Triticum aestivum L. Differing in Resistance to Abiotic Stressors [PDF]

Journal of Stress Physiology & Biochemistry, 2017
Effects of high (+400C, 2 h) and low positive (+40C, 2 h) temperatures on lipoxygenase activity in varieties of Triticum aestivum L. differing in their resistance to abiotic stressors have been analyzed.
L.M. Babenko
doaj  

Data on expression of lipoxygenases-5 and -12 in the normal and acetaminophen-damaged liver

Data in Brief, 2016
Here we present additional data on the expression of lipoxygenases -5 and -12 in the normal and acetaminophen-damaged liver, which are associated with our manuscript recently published in Chemico-Biological Interactions on lipid metabolism and eicosanoid
Maria Suciu, Alexandra T. Gruia, Dragos V. Nica, Seyed M.R. Azghadi, Ani A. Mic, Felix A. Mic   +5 more
doaj   +1 more source

Differences in Grain Microstructure and Proteomics of a Broad Bean (Vicia faba L.) Landrace Cixidabaican in China Compared with Lingxiyicun Introduced from Japan

Plants, 2021
In response to the germplasm resources’ conservation in China, the characters of a superior landrace of broad bean (Vicia faba L.) Cixidabaican (CX) were identified, compared with Lixiyicun (LX) introduced from Japan.
Pengfei Hao, Yaming Zhu, Qidong Feng, Zhuqun Jin, Feibo Wu   +4 more
doaj   +1 more source

12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γ Counterregulated-Mediator of Allergic Airway Inflammation

Mediators of Inflammation, 2010
Interleukin-13 and interferon-γ are important effectors of T-helper cells. Interleukin-13 increases expression of the arachidonic acid-metabolizing enzyme, 15-lipoxygenase-1, in a variety of cell types.
Alexa R. Lindley, Margaret Crapster-Pregont, Yanjun Liu, Douglas A. Kuperman   +3 more
doaj   +1 more source

Feedback activation of ferrous 5-lipoxygenase during leukotriene synthesis by coexisting linoleic acid

Journal of Lipid Research, 2007
Ferrous lipoxygenases seem to be activated through a feedback control mechanism via FA hydroperoxides generated from PUFAs by partially existing ferric lipoxygenases. However, during leukotriene synthesis, feedback activation of ferrous 5-lipoxygenase in
Tokuko Takajo, Kazunori Tsuchida, Koichi Ueno, Ichiro Koshiishi   +3 more
doaj   +1 more source

Green Synthesis and Characterization of Silver Nanoparticles Using a Lythrum salicaria Extract and In Vitro Exploration of Their Biological Activities

Life, 2022
This research describes an eco-friendly green route for the synthesis of AgNPs using an aqueous extract of Lythrum salicaria. Taguchi design was used to optimize the synthesis method, taking into account various working conditions. The optimum parameters
Andreia Corciovă, Cornelia Mircea, Ana Flavia Burlec, Adrian Fifere, Ioana Turin Moleavin, Alexandra Sarghi, Cristina Tuchiluș, Bianca Ivănescu, Irina Macovei   +8 more
doaj   +1 more source

Comprehensive Characterization of Fruit Volatiles and Nutritional Quality of Three Cucumber (Cucumis sativus L.) Genotypes from Different Geographic Groups after Bagging Treatment

Foods, 2020
Bagging is widely practiced to produce high quality and unblemished fruit; however, little is currently known about the effect of bagging on flavor and nutritional quality of cucumber fruits.
Nan Shan, Zengyu Gan, Jing Nie, Huan Liu, Zhenyu Wang, Xiaolei Sui   +5 more
doaj   +1 more source

Immunolocalization of Lipoxygenase in the Anther Wall Cells of Lathyrus undulatus Boiss. during Programmed Cell Death

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2011
Lipoxygenase catalyzes oxygenation of long chain fatty acids to hydroperoxides and is involved in the degradation of membranes occuring in some types of programmed cell death (PCD).
Filiz VARDAR, Meral ÜNAL
doaj   +1 more source

Biochemical changes of lipids in plant foods and feeds. II. Lipid hydroperoxides metabolism

Grasas y Aceites, 1991
The enzymes of the lipoxygenase pathway in plant foods are reviewed. This part analyzes the enzymes related to the descomposition or transformation of the lipidic hydroperoxides.
R. Zamora, F. J. Hidalgo, M. Alaiz
doaj   +1 more source