Results 31 to 40 of about 63,955 (309)

13-(S)-Hydroxyoctadecadienoic acid (13-HODE) incorporation and conversion to novel products by endothelial cells1

Journal of Lipid Research, 1999
13(S)-Hydroxy-[12,13-3H]octadecadienoic acid (13-HODE), a linoleic acid oxidation product that has vasoactive properties, was rapidly taken up by bovine aortic endothelial cells.
Xiang Fang, Terry L. Kaduce, Arthur A. Spector   +2 more
doaj   +1 more source

Image_5_Five-lipoxygenase-activating protein-mediated CYLD attenuation is a candidate driver in hepatic malignant lesion.tif

, 2022
Hepatocellular carcinoma (HCC) is an inflammation-associated cancer. However, the lipid pro-inflammatory mediators have only been seldom investigated in HCC pathogenesis. Cylindromatosis (CYLD) attenuation is involved in hepatocarcinogenesis.
Christian Bréchot (318691), Xue-hua Zheng (13181748), Dan-hua Zhu (13181754), Xiao-ping Zheng (13181751), Kun-kai Su (13181745), Yi-jia Lou (2836781), Rong Huang (298496), Yan-hong Zhang (13181757), Jing-jing Tao (13181760), Lan-juan Li (13181763)   +9 more
core   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Quasi‐Lipoxygenase Activity of Haemoglobin [PDF]

European Journal of Biochemistry, 1981
Haemoglobin catalyses at low concentrations (0.01–1 μM) a quasi‐lipoxygenase reaction with remarkably high substrate specificity. Formation of lipohydroperoxides was demonstrated only with free 9‐cis,12‐cis‐octadecadienoic acid (Linoleic acid), its glycerol monoester, or 9‐cis,12‐cis‐octadecadienol (Linoleoyl alcohol).
H, Kühn, R, Götze, T, Schewe, S M, Rapoport   +3 more
openaire   +2 more sources

CD69 is a TGF-β/1α,25-dihydroxyvitamin D3 target gene in monocytes

, 2013
CD69 is a transmembrane lectin that can be expressed on most hematopoietic cells. In monocytes, it has been functionally linked to the 5-lipoxygenase pathway in which the leukotrienes, a class of highly potent inflammatory mediators, are produced ...
Thea K Wöbke, Thea K. Wöbke, Bernd L. Sorg, Dieter Steinhilber, Wöbke, Thea Katharina, Andreas von Knethen, Bernd L Sorg, Sorg, Bernd L., Knethen, Andreas von, Steinhilber, Dieter   +9 more
core   +1 more source

Image_6_Five-lipoxygenase-activating protein-mediated CYLD attenuation is a candidate driver in hepatic malignant lesion.tif

, 2022
Hepatocellular carcinoma (HCC) is an inflammation-associated cancer. However, the lipid pro-inflammatory mediators have only been seldom investigated in HCC pathogenesis. Cylindromatosis (CYLD) attenuation is involved in hepatocarcinogenesis.
Christian Bréchot (318691), Xue-hua Zheng (13181748), Dan-hua Zhu (13181754), Xiao-ping Zheng (13181751), Kun-kai Su (13181745), Yi-jia Lou (2836781), Rong Huang (298496), Yan-hong Zhang (13181757), Jing-jing Tao (13181760), Lan-juan Li (13181763)   +9 more
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Evaluation of Polyphenol Content and Lipoxygenase Activity in Selected Oil Cakes in Terms of Their Valorization

Biology and Life Sciences Forum, 2023
Oil cakes are pomace that is a by-product of pressing oil from oilseeds. Due to the content of bioactive ingredients, there is more and more talk about their valorization through use in human and animal nutrition as well as microbiological processes ...
Jolanta Małajowicz, Anna Dziedzic, Paulina Goleń, Tomasz Stepaniuk   +3 more
doaj   +1 more source

Image_2_Five-lipoxygenase-activating protein-mediated CYLD attenuation is a candidate driver in hepatic malignant lesion.tif

, 2022
Hepatocellular carcinoma (HCC) is an inflammation-associated cancer. However, the lipid pro-inflammatory mediators have only been seldom investigated in HCC pathogenesis. Cylindromatosis (CYLD) attenuation is involved in hepatocarcinogenesis.
Christian Bréchot (318691), Xue-hua Zheng (13181748), Dan-hua Zhu (13181754), Xiao-ping Zheng (13181751), Kun-kai Su (13181745), Yi-jia Lou (2836781), Rong Huang (298496), Yan-hong Zhang (13181757), Jing-jing Tao (13181760), Lan-juan Li (13181763)   +9 more
core   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source