Results 61 to 70 of about 3,490 (194)
Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Cancer Communications, Volume 45, Issue 11, Page 1456-1495, November 2025.Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu +4 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 29, Issue 22, November 2025.ABSTRACT Long non‐coding RNAs (lncRNAs) play important roles in colorectal cancer (CRC) progression. However, the biological function and regulatory mechanism of small nucleolar RNA host gene 26 (SNHG26) in CRC remain largely unexplored. SNHG26 expression was analysed in CRC tissues and cell lines using quantitative real‐time PCR (qRT‐PCR).
Ziang Wan, Shan Gao
wiley +1 more source
Cell Death Discovery, 2022 Esophageal carcinoma (ESCA) is a common type of cancer with high mortality. Cuproptosis is a new type of cell death and is characterized by the dependence on mitochondrial respiration and protein lipoylation.
Runmin Jiang +6 more
doaj +1 more source
Advanced Science, Volume 12, Issue 37, October 6, 2025.This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li +8 more
wiley +1 more source
p32 regulates glycometabolism and TCA cycle to inhibit ccRCC progression via copper-induced DLAT lipoylation oligomerization [PDF]
, 2023 Shaoping Tian +10 more
openalex +1 more source
Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management
MedComm, Volume 6, Issue 10, October 2025.Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu +5 more
wiley +1 more source
FDX1 regulates cellular protein lipoylation through direct binding to LIAS [PDF]
, 2023 Margaret Dreishpoon +8 more
openalex +3 more sources
Isolation of the Cadmium Derivative of Lipoyl Dehydrogenase
Journal of Biological Chemistry, 1971 Abstract Reduced lipoamide dehydrogenase reacts with cadmium ion to form a moderately stable compound characterized by 1 g atom of cadmium bound per mole of flavin adenine dinucleotide, a modified spectrum in the visible region, and altered reactivity with electron acceptor substrates.
A M, Stein, J H, Stein
openaire +2 more sources
Knockout studies reveal an important role of Plasmodium lipoic acid protein ligase A1 for asexual blood stage parasite survival. [PDF]
PLoS ONE, 2009 Lipoic acid (LA) is a dithiol-containing cofactor that is essential for the function of alpha-keto acid dehydrogenase complexes. LA acts as a reversible acyl group acceptor and 'swinging arm' during acyl-coenzyme A formation.
Svenja Günther +2 more
doaj +1 more source
Liver‐specific lncRNAs associated with liver cancers
FEBS Open Bio, Volume 15, Issue 9, Page 1383-1405, September 2025.Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina +3 more
wiley +1 more source