Results 61 to 70 of about 4,213 (194)

Lipidomic Analysis of Plastidial Octanoyltransferase Mutants of Arabidopsis thaliana [PDF]

open access: yes, 2019
International audiencePlant de novo fatty acid synthesis takes place in the plastid using acetyl-coenzyme A (acetyl-CoA) as the main precursor. This first intermediate is produced from pyruvate through the action of the plastidial pyruvate dehydrogenase ...
Acket, Sébastien   +8 more
core   +3 more sources

Volumetric Engineered 3D Drug Reservoir Against Diabetic Implant Infection via Cuproptosis‐Like Bacterial Death and Hunger‐Triggered Maintenance of Mitochondrial Integrity

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li   +8 more
wiley   +1 more source

Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu   +5 more
wiley   +1 more source

Isolation of the Cadmium Derivative of Lipoyl Dehydrogenase

open access: yesJournal of Biological Chemistry, 1971
Abstract Reduced lipoamide dehydrogenase reacts with cadmium ion to form a moderately stable compound characterized by 1 g atom of cadmium bound per mole of flavin adenine dinucleotide, a modified spectrum in the visible region, and altered reactivity with electron acceptor substrates.
A M, Stein, J H, Stein
openaire   +2 more sources

Lipoate Metabolism in Staphylococcus Aureus Pathogenesis [PDF]

open access: yes, 2016
Lipoate is an essential cofactor of several proteins involved in cellular energy homeostasis and catabolism. Lipoate metabolism has been linked to pathogenesis in some microbial species, but its role in Staphylococcus aureus infections had not been ...
Zorzoli, Maria Azul
core   +1 more source

Liver‐specific lncRNAs associated with liver cancers

open access: yesFEBS Open Bio, Volume 15, Issue 9, Page 1383-1405, September 2025.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina   +3 more
wiley   +1 more source

Lipoic acid protein ligases in Plasmodium spp. [PDF]

open access: yes, 2008
Protozoan parasites of the genus Plasmodium are the causative agent of malaria. The four human pathogenic species infect more than 500 million people each year, causing the death of at least 1 million people.
Günther, Svenja
core   +1 more source

Clinical and biochemical characterization of four patients with mutations in ECHS1 [PDF]

open access: yes, 2015
Short-chain enoyl-CoA hydratase (SCEH, encoded by ECHS1) catalyzes hydration of 2-trans-enoyl-CoAs to 3(S)-hydroxy-acyl-CoAs. SCEH has a broad substrate specificity and is believed to play an important role in mitochondrial fatty acid oxidation and in ...
Alberto Burlina   +16 more
core   +1 more source

A Mitochondria‐Targeted Nanozyme Platform for Multi‐Pathway Tumor Therapy via Ferroptosis and Cuproptosis Regulation

open access: yesAdvanced Science, Volume 12, Issue 36, September 25, 2025.
This work reports a mitochondria‐targeted nanozyme platform, MIL‐Cu1.8S‐TPP/FA, which induces potent cuproptosis via localized delivery of Cu1.8S nanodots to mitochondria. Surface‐anchoring these nanodots onto MIL‐88B metal‐organic frameworks enhances both passive and active tumor targeting.
Chenguang Liu   +8 more
wiley   +1 more source

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