Results 81 to 90 of about 4,273 (194)
Multiple molecular mechanisms cause reproductive isolation between three yeast species. [PDF]
PLoS Biology, 2010 Nuclear-mitochondrial conflict (cytonuclear incompatibility) is a specific form of Dobzhansky-Muller incompatibility previously shown to cause reproductive isolation in two yeast species.
Jui-Yu Chou +4 more
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MedComm, Volume 6, Issue 12, December 2025.Radiation‐induced biological effects are an extremely complex and extensive mechanism that involves multiple aspects of physiological activities in organisms. In the medical field, utilizing the damaging effects of radiation to treat tumors is a commonly employed therapeutic approach.
Zhihe Hu +5 more
wiley +1 more source
Lipoate Metabolism in Staphylococcus Aureus Pathogenesis [PDF]
, 2016 Lipoate is an essential cofactor of several proteins involved in cellular energy homeostasis and catabolism. Lipoate metabolism has been linked to pathogenesis in some microbial species, but its role in Staphylococcus aureus infections had not been ...
Zorzoli, Maria Azul
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Isolation of the Cadmium Derivative of Lipoyl Dehydrogenase
Journal of Biological Chemistry, 1971 Abstract Reduced lipoamide dehydrogenase reacts with cadmium ion to form a moderately stable compound characterized by 1 g atom of cadmium bound per mole of flavin adenine dinucleotide, a modified spectrum in the visible region, and altered reactivity with electron acceptor substrates.
A M, Stein, J H, Stein
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Advanced Science, Volume 12, Issue 43, November 20, 2025.A titanium implant coating integrating berberine and copper‐doped strontium titanate leverages ultrasound to compromise bacterial membranes and induce cuproptosis‐like death. This approach resolves S. aureus infections in osteomyelitis models while suppressing inflammation and promoting osseointegration, demonstrating a dual‐functional strategy against
Guannan Zhang +8 more
wiley +1 more source
mBio, 2018 Lipoate is a redox active cofactor that is covalently bound to key enzymes of oxidative metabolism. Plasmodium falciparum is auxotrophic for lipoate during the intraerythrocytic stages, but it is not known whether lipoate attachment to protein is ...
Hugo Jhun +2 more
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Cell Death Discovery, 2022 Esophageal carcinoma (ESCA) is a common type of cancer with high mortality. Cuproptosis is a new type of cell death and is characterized by the dependence on mitochondrial respiration and protein lipoylation.
Runmin Jiang +6 more
doaj +1 more source
Evidence for two protein‐lipoylation activities in Escherichia coli [PDF]
FEBS Letters, 1991 The lipoate acyltransferase subunits of the 2‐oxo acid dehydrogenase complexes are post‐translationally modified with one or more covalently‐bound lipoyl cofactors. Two distinct lipoate‐protein ligase activities, LPL‐A and LPL‐B, have been detected in E. coli by their ability to modify purified lipoyl apo‐domains of the bacterial pyruvate dehydrogenase
Brookfield, Dawn E. +4 more
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Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Cancer Communications, Volume 45, Issue 11, Page 1456-1495, November 2025.Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu +4 more
wiley +1 more source
Lipoic acid protein ligases in Plasmodium spp. [PDF]
, 2008 Protozoan parasites of the genus Plasmodium are the causative agent of malaria. The four human pathogenic species infect more than 500 million people each year, causing the death of at least 1 million people.
Günther, Svenja
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