Results 231 to 240 of about 201,821 (348)

Liquid biopsy in lung cancer screening: rationale, progress, opportunities and challenges. [PDF]

Clin Exp Med
Li C, Jiang H, Sun X, Meng F, Cui P, Wang G, Liu C, Cai S, Duan F, Su Q, Zhao C.   +10 more
europepmc   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Liquid biopsy in biliary tract cancers: early diagnosis, precision therapy, and prognostic evaluation. [PDF]

Front Oncol
Wu G, Xu X, Zhang H, Peng L, Liu C.
europepmc   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Liquid Biopsy in Lung Cancer: Tracking Resistance to Targeted Therapies. [PDF]

Cancers (Basel)
Urtecho SB, Jimenez Munarriz B, Rabey MR, Leighl NB.   +3 more
europepmc   +1 more source

Supplementary Figure S8 from Urinary Metabolite Diagnostic and Prognostic Liquid Biopsy Biomarkers of Lung Cancer in Nonsmokers and Tobacco Smokers

Bhavik Dalal, Takeshi Tada, Daxesh P. Patel, Sharon R. Pine, Mohammed Khan, Takahiro Oike, Yasuyuki Kanke, Amelia L. Parker, Majda Haznadar, Leila Toulabi, Kristopher W. Krausz, Ana I. Robles, Elise D. Bowman, Frank J. Gonzalez, Curtis C. Harris   +14 more
openalex   +1 more source

Circulation of rare events in the liquid biopsy for early detection of lung mass lesions [PDF]

Karen Resnick, Anya Shah, Jeremy Mason, Peter Kühn, Jorge J. Nieva, Stephanie N. Shishido   +5 more
openalex   +1 more source

Clinical Utility Versus Futility: A Tipping Point for Liquid Biopsies in Bladder Cancer [PDF]

, 2019
Erik Kouba, Liang Cheng
openalex   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source

Cancer in a drop: Liquid biopsy highlights from San Antonio Breast Cancer Symposium (SABCS) 2024

The Journal of Liquid Biopsy
Letizia Pontolillo, Mohamed A. Gouda, Konstantinos Venetis, Eleonora Nicolò, Carolina Reduzzi   +4 more
doaj   +1 more source