Results 271 to 280 of about 201,821 (348)

A Microfluidic Digital Shutter of Liquid–Liquid Interface for Fabrication of Multifaceted Hydrogel Microfiber Structure

Advanced Science, EarlyView.
A programmable passive digital shutter based on multiphase liquid–liquid interface dynamics is introduced for precise fabrication of hydrogel microfibers. By modulating the shutter operation, microfibers with tunable geometry—including linear, helical, tadpole‐like, and spherical forms—are produced.
Dongrui Zhang, Jiangyue Liu, Hao Ye, Yu Shen, Haoran Su, Zhuqing Liang, Kexin Li, Xing Zhang, Shiyi Yang, Yunfei Lu, Zhexi Zhang, Sihang Liu, Yi Huang, Xiao Liu, Yubo Fan   +14 more
wiley   +1 more source

Lipocalin 2 as a potential liquid biopsy marker for early detection of bladder cancer. [PDF]

Clin Transl Med
Jeong MS, Mun JY, Yang GE, Baek SW, Lee SY, Yun SH, Kim SI, Kim JJ, Yoon SY, Nam JK, Choi YH, Goh HJ, Kim TN, Leem SH.   +13 more
europepmc   +1 more source

Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples

Advanced Science, EarlyView.
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen, Yi Zhang, Yu‐Jie Yan, Meng‐Ting Zhang, Jian‐Bo Chen, Yi‐Rong Jiang, Jie Wu, Hui‐Feng Wang, Jian‐Zhang Pan, Zhi‐Gang Chen, Jian Huang, Qun Fang   +11 more
wiley   +1 more source

Transforming Cancer Diagnostics: The Emergence of Liquid Biopsy and Epigenetic Markers. [PDF]

MedComm (2020)
Saha D, Kanjilal P, Kaur M, Menon SV, Ashraf A, Kumar MR, Alqahtani T, Atteri S, Uti DE, Dhara B.   +9 more
europepmc   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

A multi-centre performance evaluation of a commercially developed liquid biopsy for the earlier detection of brain tumours. [PDF]

ESMO Open
Brennan PM, Cameron JM, Eustace D, Butler HJ, Sala A, Lazarus A, Antoniou G, Palmer DS, Gray E, Kerrie C, McDonald S, Black P, Sheraz S, Adekoya I, Jakola A, Denes A, Jenkinson MD, Jones J, Pendered S, Koljenovic S, Zwaenepoel K, Sieben A, Ahmed M, Feyen B, Mathew RK, Coils C, Ismail A, Phang I, Brown A, Patel S, Weiss T, Westarp PW, Kopp A, Baker MJ.   +33 more
europepmc   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Νovel methylation biomarkers in liquid biopsy and classifying biosignatures for the clinical management of breast cancer. [PDF]

Breast Cancer Res
Panagopoulou M, Papadaki MA, Karaglani M, Theodosiou T, Michaelidou K, Baritaki S, Tsamardinos I, Kakolyris S, Agelaki S, Chatzaki E.   +9 more
europepmc   +1 more source

Serial Liquid Biopsy [PDF]

, 2020
openaire   +1 more source