Results 81 to 90 of about 3,019,224 (363)

Optical nanomaterial-based detection of biomarkers in liquid biopsy

Journal of Hematology & Oncology
Liquid biopsy, which is a minimally invasive procedure as an alternative to tissue biopsy, has been introduced as a new diagnostic/prognostic measure.
Young Jun Kim, Won‐Yeop Rho, Seung-min Park, Bong-Hyun Jun   +3 more
semanticscholar   +1 more source

EGFR inhibitor as second-line therapy in a patient with mutant RAS metastatic colorectal cancer: circulating tumor DNA to personalize treatment [PDF]

, 2018
A 47-year-old male patient presented in March 2016 to our unit with a palpable painless left supraclavicular mass. A whole-body contrastenhanced computed tomography (CT) scan revealed a left supraclavicular lymphadenopathy, transverse colon thickening ...
Cortesi, Enrico, Gazzaniga, Paola, Raimondi, Cristina, Urbano, Federica   +3 more
core   +1 more source

Liquid biopsy techniques and lung cancer: diagnosis, monitoring and evaluation

Journal of experimental & clinical cancer research : CR
Lung cancer stands as the most prevalent form of cancer globally, posing a significant threat to human well-being. Due to the lack of effective and accurate early diagnostic methods, many patients are diagnosed with advanced lung cancer.
Fei Ren, Qian Fei, Kun Qiu, Yuanjie Zhang, Heyang Zhang, Lei Sun   +5 more
semanticscholar   +1 more source

Exosomes as a new frontier of cancer liquid biopsy

Molecular Cancer, 2022
Liquid biopsy, characterized by minimally invasive detection through biofluids such as blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and prognosis prediction.
Dan Yu, Yixin Li, Maoye Wang, Jianmei Gu, Wenrong Xu, Huisi Cai, Xinjian Fang, Xu Zhang   +7 more
semanticscholar   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Exosomal circRNAs as promising liquid biopsy biomarkers for glioma

Frontiers in Immunology, 2023
Liquid biopsy strategies enable the noninvasive detection of changes in the levels of circulating biomarkers in body fluid samples, providing an opportunity to diagnose, dynamically monitor, and treat a range of diseases, including cancers.
Xiaoke Wu, M. Shi, Y. Lian, Haifeng Zhang   +3 more
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Implementation of and Early Outcomes From Anal Cancer Screening at a Community-Engaged Health Care Facility Providing Care to Nigerian Men Who Have Sex With Men. [PDF]

, 2019
PurposeAnal cancer risk is substantially higher among HIV-infected men who have sex with men (MSM) as compared with other reproductive-age adults, but screening is rare across sub-Saharan Africa.
Baral, Stefan D, Bentzen, Søren M, Blattner, William A, Charurat, Manhattan E, Crowell, Trevor A, Cullen, Kevin J, Darragh, Teresa M, Dauda, Wuese, Jibrin, Paul, Madukwe, Jonathan, Ndembi, Nicaise, Nnaji, Chinedu H, Nowak, Rebecca G, Olaomi, Oluwole, Palefsky, Joel M, TRUST/RV368 Study Group   +15 more
core   +1 more source

Liquid Biopsy in Lung Cancer: Biomarkers for the Management of Recurrence and Metastasis

International Journal of Molecular Sciences, 2023
Liquid biopsies have emerged as a promising tool for the detection of metastases as well as local and regional recurrence in lung cancer. Liquid biopsy tests involve analyzing a patient’s blood, urine, or other body fluids for the detection of biomarkers,
Vanessa G P Souza, Aisling Forder, Liam J Brockley, Michelle E. Pewarchuk, N. Telkar, R. P. de Araújo, Jessica Trejo, Katya Benard, A. L. Seneda, I. W. Minutentag, Melis Erkan, G. Stewart, E. Hasimoto, C. Garnis, W. Lam, Victor D. Martinez, P. Reis   +16 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source