Bioanalysis of amphetamines in alternative matrices using a sensitive and validated liquid chromatography-tandem mass spectrometry method and its application to real samples. [PDF]
Makhdoom HS, Abid AI, Khan NUH, Abbas Z.
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Liquid chromatography-tandem mass spectrometry technology revealed differences in serum metabolites between rheumatoid arthritis patients in different seasons. [PDF]
Peng J +8 more
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Determination of Pyrrolizidine Alkaloids and Their N‑Oxides in Bee Pollen by Accelerated Solvent Extraction Followed by Magnetic Covalent Organic Framework-Based Offline Purification and Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry. [PDF]
Wang Y +5 more
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Tissue Proteomics of Feline Mammary Carcinoma: Differences in Protein Profiles Among Histological Grades Using Liquid Chromatography-Tandem Mass Spectrometry. [PDF]
Aruvornlop P +7 more
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Liquid Chromatography–Tandem Mass Spectrometry for Clinical Diagnostics
Mass spectrometry is a powerful analytical tool used for the analysis of a wide range of substances and matrices; it is increasingly utilized for clinical applications in laboratory medicine. This Primer includes an overview of basic mass spectrometry concepts, focusing primarily on tandem mass spectrometry.
William Clarke +2 more
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Determination of dalcetrapib by liquid chromatography–tandem mass spectrometry
Journal of Pharmaceutical and Biomedical Analysis, 2012The cholesteryl ester transfer protein modulator dalcetrapib is currently under development for the prevention of dyslipidemia and cardiovascular disease. Dalcetrapib, a thioester, is rapidly hydrolyzed in vivo to the corresponding thiophenol which in turn is further oxidized to the dimer and mixed disulfides (where the thiophenol binds to peptides ...
Katja, Heinig +9 more
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A liquid chromatography tandem mass spectrometry method for plasma glucagon
Analytical Biochemistry, 2023Glucagon is a peptide involved in controlling the body's blood glucose levels. The majority of analytical methods used for its quantitation are based on immunoassays that suffer from cross-reactivity with other peptides. For accurate routine analysis a liquid chromatography tandem mass spectrometry (LC-MSMS) was developed.
Van Long, Nguyen +3 more
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Liquid chromatography tandem mass spectrometry in the clinical laboratory
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2014Clinical laboratory medicine has seen the introduction and evolution of liquid chromatography tandem mass spectrometry in routine clinical laboratories over the last 10–15 years. There still exists a wide diversity of assays from very esoteric and highly specialist manual assays to more simplified kit-based assays.
Joanne E, Adaway +2 more
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Mediator lipidomics by liquid chromatography-tandem mass spectrometry
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2017Comprehensive quantitative analysis of lipid mediators using liquid chromatography-tandem mass spectrometry is an effective strategy in the elucidation of disease mechanisms; but technically, it has been and is still a great challenge to achieve reliable datasets that cover variety of lipid metabolites contained at trace levels in complex biological ...
Yoshihiro, Kita +2 more
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