Results 221 to 230 of about 177,363 (264)
Some of the next articles are maybe not open access.
Liquid Chromatography-Tandem Mass Spectrometry for Quantitation of Serum Pentobarbital
2023Pentobarbital is a short-acting barbiturate with anticonvulsant and sedative-hypnotic properties. Pentobarbital may be used to induce sedation, control seizures, induce coma, and to manage patients with traumatic brain injury. In traumatic brain injury, use of pentobarbital is known to reduce both cerebral blood flow and oxygen consumption, which ...
Hafiz Anas, Yahya, Patrick B, Kyle
openaire +2 more sources
Quantitation of Tapentadol by Liquid Chromatography: Tandem Mass Spectrometry
2018Tapentadol is an orally active analgesic with a similar structure to tramadol. Its primary mechanism of action is agonist action on the mu-opioid receptor. The method described here quantitates tapentadol in the whole blood using a matching deuterated internal standard, extraction via a protein "crash" with acetonitrile, followed by analysis using ...
Graham R, Jones, Russell P, Handy
openaire +2 more sources
Determination of Furosine in Hair by Liquid Chromatography-Tandem Mass Spectrometry
Biomedical Chromatography, 1997A sensitive and reliable analytical method for determining furosine in hair has been developed using liquid chromatography-tandem mass spectrometry. Fructose-N(omega)-formyl-d4-DL-lysine was synthesized and used as an internal standard. By the present method, glycated lysine levels in hair could be determined as fructose-lysine in only 0.1 mg of hair ...
A, Takemura +5 more
openaire +2 more sources
Chromatographia, 1998
A rapid method based on liquid chromatography and thermospray mass spectrometry without any derivatization or pre-purification steps has been developed for the identification and quantification of cannabinoids in drugs from cannabis plants. The extracts were separated on a C18 reversed-phase column with an acidic acetonitrile-water gradient.
Ndjoko, K. +2 more
openaire +3 more sources
A rapid method based on liquid chromatography and thermospray mass spectrometry without any derivatization or pre-purification steps has been developed for the identification and quantification of cannabinoids in drugs from cannabis plants. The extracts were separated on a C18 reversed-phase column with an acidic acetonitrile-water gradient.
Ndjoko, K. +2 more
openaire +3 more sources
Determination of salivary cortisol by liquid chromatography-tandem mass spectrometry
Scandinavian Journal of Clinical and Laboratory Investigation, 2009Late evening salivary cortisol concentrations are increasingly used as a screening test in suspected Cushing's syndrome partly because of easy sample collection. The cortisol immunoassays are prone to interference by cross-reacting steroids and therefore there is a need for improvement.
Ursula, Turpeinen +2 more
openaire +2 more sources
Analysis of Hypoglycemic Drugs by Liquid Chromatography-Tandem Mass Spectrometry
2023A rapid and simple method to measure oral hypoglycemic agents is essential in the evaluation of a patient with spontaneous hypoglycemia. As a result, a robust high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was developed for the qualitative detection of first-generation sulfonylureas (e.g., chlorpropamide, tolazamide,
Paul J, Jannetto, Loralie J, Langman
openaire +2 more sources
Analysis of RNA modifications by liquid chromatography–tandem mass spectrometry
Methods, 2016The analysis of RNA modifications is of high importance in order to address a wide range of biological questions. Therefore, a highly sensitive and accurate method such as liquid chromatography-tandem mass spectrometry (LC-MS/MS) has to be available.
Kathrin Thüring +3 more
openaire +2 more sources
Determination of kepone in water by liquid chromatography-tandem mass spectrometry
Chinese Journal of Chromatography, 2014An analytical procedure for the determination of kepone in water was described. Water samples were extracted by liquid-liquid extraction, and then cleaned-up. Chromatographic separation was performed on an Eclipse plus C18 column (100 mm x 2.1 mm, 3.5 microm) with gradient elution using acetonitrile and water at a flow rate of 0.3 mL/min.
Li, Zhou +7 more
openaire +2 more sources
Investigation of the biotransformation of osthole by liquid chromatography/tandem mass spectrometry
Journal of Pharmaceutical and Biomedical Analysis, 2013Osthole is an active ingredient and one of the major coumarin compounds that were identified in the genus Cnidium moonnieri (L.) Cussion, the fruit of which was used as traditional Chinese medicine to treat male impotence, ringworm infection and blood stasis conventionally.
Li, Jie, Chan, Wan
openaire +3 more sources
Quantification of fluoroquinolones in wastewaters by liquid chromatography-tandem mass spectrometry
Environmental Pollution, 2020Antibiotics are the most consumed therapeutic classes worldwide and are released to the environment in their original form as well as potentially active metabolites and/or degradation products. Consequences of the occurrence of these compounds in the environment are primarily related to bacterial resistance development.
Maia, Alexandra S. +4 more
openaire +3 more sources