Results 51 to 60 of about 3,375,594 (236)

Advances in native high-performance liquid chromatography and intact mass spectrometry for the characterization of biopharmaceutical products.

Journal of Separation Science, 2018
The characterization of biotherapeutics represents a major analytical challenge. This review discusses the current state-of-the-art in analytical technologies to profile biopharma products under native conditions, i.e., the protein three dimensional ...
Marco Tassi, J. De Vos, S. Chatterjee, F. Sobott, J. Bones, S. Eeltink   +5 more
semanticscholar   +1 more source

Liquid chromatography-tandem mass spectrometry - Application in the clinical laboratory [PDF]

, 2003
This review provides a concise survey of liquid chromatography tandem mass spectrometry (LCTMS) as an emerging technology in clinical chemistry. The combination of two mass spectrometers with an interposed collision cell characterizes LCTMS as an ...
Ford RE, Kushnir MM, Kushnir MM, Muck W, Murdter TE, Rashed MS, Streit F, Taylor RL   +7 more
core   +1 more source

High-performance Liquid Chromatography Analysis of Nebivolol and Amlodipine and Some Related Compounds in Synthetic Mixture

Bezmiâlem Science, 2021
Objective:This study aimed to develop and validate a method using a high-performance liquid chromatography (HPLC) to perform a quantitative analysis of nebivolol (NEB) and amlodipine (AML) along with some related substances in the synthetic mixture ...
Cem ÖNAL, Kadir ALUÇ, Çiğdem ALUÇ, Armağan ÖNAL   +3 more
doaj   +1 more source

Determination of DNA base composition by reversed-phase high-performance liquid chromatography

, 1984
DNA base composition was determined by reversed-phase high-performance liquid chromatography (HPLC). DNA was hydrolysed into nucleosides with nuclease P1 and bacterial alkaline phosphatase.
J. Tamaoka, K. Komagata
semanticscholar   +1 more source

Optimizing separations in online comprehensive two‐dimensional liquid chromatography

Journal of Separation Science, 2017
Online comprehensive two‐dimensional liquid chromatography has become an attractive option for the analysis of complex nonvolatile samples found in various fields (e.g. environmental studies, food, life, and polymer sciences).
Bob W. J. Pirok, Andrea F. G. Gargano, P. Schoenmakers   +2 more
semanticscholar   +1 more source

Predicting drug penetration across the blood-brain barrier: comparison of micellar liquid chromatography and immobilized artificial membrane liquid chromatography [PDF]

, 2012
Several in vitro methods have been investigated for mimicking drug penetration across the blood-brain barrier (BBB) into the central nervous system (CNS).
De Vrieze, Mike, Lynen, Frederic, Sandra, Patrick   +2 more
core  

Comparison of enhanced fluidity liquid chromatography with liquid chromatography for enantioseparation of selected γ-lactam derivatives

Journal of Chromatography Open, 2022
The present paper describes the study of eight racemic γ-lactam derivatives with the goal of comparing three modes of liquid chromatography which are the reversed-phase mode, the normal-phase mode and the polar organic solvent chromatography mode with ...
Anca-Elena Dascalu, Alina Ghinet, Muriel Billamboz, David Speybrouck, Emmanuelle Lipka   +4 more
doaj  

Cloud point extraction coupled with back extraction: a green methodology in analytical chemistry

Forensic Sciences Research, 2021
Recently, cloud point extraction (CPE) coupled with back extraction (BE) has been suggested as a promising alternative to liquid-liquid extraction. In CPE, non-ionic surfactants in aqueous solutions form micelles and the solution becomes turbid when ...
Shivpoojan Kori
doaj   +1 more source

Lipid Peroxidation Process in Meat and Meat Products: A Comparison Study of Malondialdehyde Determination between Modified 2-Thiobarbituric Acid Spectrophotometric Method and Reverse-Phase High-Performance Liquid Chromatography

Molecules, 2017
The aim of this work was to compare the methods of malondialdehyde detection, as the main secondary product of the lipid peroxidation process, in meat and meat products.
Anna Reitznerová, Monika Šuleková, J. Nagy, S. Marcinčák, B. Semjon, M. Čertík, T. Klempová   +6 more
semanticscholar   +1 more source

STRUCTURE OF METHYLPHEOPHORBIDE-RCI [PDF]

, 1986
he methanolic extract of the cyanobacterium (blue-green alga) Spirulina geitleri has been treated with methanolic acid to convert all chlorophyllous pigments to their methylpheophorbides.
Budzikiewicz H., Dismukes G. C., Dornemann D., Dornemann D., Dornemann D., Feher G., Fischer H., Fuhrhop J.H., Harrison J. E., Hynninen P. H., Hynninen P. H., Klimov V. V., Knaff D. B., Moore R. E., Norris J.R., O'Malley P. J., Schaffernicht H., Schatz G. H., Scheer H., Scheer H., Senger H., Svec W. A., Thomas J. A., Vacek K., Vierling E., Wasielewski M., Wu S.M., Yuasa M.   +27 more
core   +1 more source