Results 61 to 70 of about 571,961 (344)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Nano-Objects and Ions in Liquid Crystals: Ion Trapping Effect and Related Phenomena

open access: yesCrystals, 2015
The presence of ions in liquid crystals is one of the grand challenges that hinder the application of liquid crystals in various devices, which include advanced 3-D and flexible displays, tunable lenses, etc.
Yuriy Garbovskiy, Iryna Glushchenko
doaj   +1 more source

James Fergason, a Pioneer in Advancing of Liquid Crystal Technology [PDF]

open access: yes, 2013
James Lee Fergason (1934 - 2008) focused his research on the liquid crystals. His studies correspond to a relevant part of the history of soft matter science and technology of liquid crystals.
Sparavigna, Amelia Carolina
core   +1 more source

How glassy are orientational dynamics of rodlike molecules near the isotropic-nematic transition?

open access: yes, 2007
In an attempt to quantitatively characterize the recently observed slow dynamics in the isotropic and nematic phase of liquid crystals, we investigate the single-particle orientational dynamics of rodlike molecules across the isotropic-nematic transition
Biman Bagchi   +8 more
core   +1 more source

Uniaxial symmetry in nematic liquid crystals [PDF]

open access: yes, 2014
Within the Landau-de Gennes theory of liquid crystals, we study theoretically the equilibrium configurations with uniaxial symmetry. We show that the uniaxial symmetry constraint is very restrictive and can in general not be satisfied, except in very ...
Lamy, Xavier
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Novel Trends in Lyotropic Liquid Crystals

open access: yesCrystals, 2020
We introduce and shortly summarize a variety of more recent aspects of lyotropic liquid crystals (LLCs), which have drawn the attention of the liquid crystal and soft matter community and have recently led to an increasing number of groups studying this ...
Ingo Dierking   +1 more
doaj   +1 more source

Thermoreversible Gel-Dispersed Liquid Crystals

open access: yesGels, 2023
A simple model is introduced to describe phase behaviours of binary mixtures of a thermoreversible gel and a low-molecular-weight liquid crystal (LC). We predict novel phase diagrams on the temperature–concentration plane, including sol–gel transition ...
Akihiko Matsuyama
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Cubic and hexagonal liquid crystals as drug carriers for the transdermal delivery of triptolide

open access: yesDrug Delivery, 2019
The purpose of this study was to develop and evaluate triptolide-loaded cubic and hexagonal liquid crystals for transdermal drug delivery systems (TDDSs).
Qian-Qian Shan   +4 more
doaj   +1 more source

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