Characterization and Transdermal Delivery of Ethosomes Loaded with Liquiritigenin and Liquiritin
Applied Chemistry for Engineering, 2015 Abstract Liquiritin and its aglycone, liquiritigenin are flavonoid found in licorice that show anti-oxidant and anti-aging properties. In this study, ethosomes loaded with hydrophobic liquiritigenin or liquiritin were prepared as a transdermal delivery system.
Na Ri Im +5 more
exaly +3 more sources
Liquiritin from Glycirrhyza Glabra L (Fabaceae) - a Natural Derived Drug, as a Potential Inhibitor for SARS-CoV-2 [PDF]
, 2021 Novel Corona virus-2 (Covid-19) is spreading and causing major damage around the globe and constantly increasing daily. There is a prerequisite of expeditious development of safe and efficient drugs for such a contagious disease.
Nimisha, Patel +5 more
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Reproductive and Developmental Medicine, 2022 . Objective:. Altered bile acid transformation induces low-grade chronic inflammation and may play an important role in the pathophysiology of polycystic ovary syndrome (PCOS). Liquiritincan regulate bile acid metabolism and anti-inflammatory properties;
Zhi Li +6 more
doaj +1 more source
Liquiritin alleviates spinal cord injury through suppression of inflammation, oxidative stress, and cell apoptosis in a rat model [PDF]
, 2021 Purpose: Liquiritin is an extract from Glycyrrhiza Radix, one of the oldest traditional Chinese herbal medicines, which is commonly used to treat various injuries and swellings.
Luo, Yongsheng +5 more
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Liquiritin inhibits MRGPRX2-mediated pseudo-allergy through the PI3K/AKT and PLCγ signaling pathways
Heliyon, 2023 Liquiritin is a natural flavone with a variety of pharmacological effects derived from the medicinal food homology plant Glycyrrhiza uralensis Fisch. As a kind of lethal allergic reactions, pseudo-allergic reactions (PARs) arise from the Mas-related G ...
Lu Wang +5 more
doaj +1 more source
Liquiritin Alleviates Pain Through Inhibiting CXCL1/CXCR2 Signaling Pathway in Bone Cancer Pain Rat
Frontiers in Pharmacology, 2020 Bone cancer pain (BCP) is an intractable clinical problem, and lacked effective drugs for treating it. Recent research showed that several chemokines in the spinal cord are involved in the pathogenesis of BCP.
Huadong Ni +10 more
doaj +1 more source
Zhenyuan Solid Drink Ameliorates Inflammation and Oxidative Stress in Isoproterenol-Induced Ischemic Myocardial Infarction via TLR4/NF-κB Pathway and PI3K/AKT1/NRF2 Pathway in Rats. [PDF]
Food Sci NutrZYSD exerts curative and preventive cardioprotection against isoproterenol‐induced myocardial infarction through synergistic interaction with probiotics, exerting antioxidant and anti‐inflammatory effects. ABSTRACT Zhenyuan Solid Drink (ZYSD) is a formulation consisting of 6 medicinal herbs that can be used as both food and medicinal materials in China.
Huang J +11 more
europepmc +2 more sources
Protective effect of liquiritin on coronary heart disease through regulating the proliferation of human vascular smooth muscle cells via upregulation of sirtuin1 [PDF]
, 2022 This study aimed to explore whether liquiritin affects the development of coronary heart disease by regulating the proliferation and migration of human vascular smooth muscle cells (hVSMCs).
Dajie Wang (11959011) +2 more
core +1 more source
Liquiritin apioside attenuates laryngeal chemoreflex but not mechanoreflex in rat pups [PDF]
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2020 Liquiritin apioside (LA), a main flavonoid component of licorice, reportedly suppresses cough responses to inhalation of aerosolized capsaicin [CAP; a stimulant to transient receptor potential vanilloid 1 (TRPV1)] in conscious guinea pigs via acting on peripheral nerves.
Wan, Wei +5 more
openaire +2 more sources
Investigation on the simultaneous inhibition of advanced glycation end products, 4-methylimidazole and hydroxymethylfurfural in thermal reaction meat flavorings by liquiritigenin, liquiritin and glycyrrhizic acid and possible pathways [PDF]
, 2023 The inhibitory effects of liquiritigenin, liquiritin and glycyrrhizic acid against the hazards during the preparation of thermal reaction beef flavoring were investigated using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).
Zhiyong He +21 more
core +1 more source