Liquiritin from Glycirrhyza Glabra L (Fabaceae) - a Natural Derived Drug, as a Potential Inhibitor for SARS-CoV-2 [PDF]
, 2021 Novel Corona virus-2 (Covid-19) is spreading and causing major damage around the globe and constantly increasing daily. There is a prerequisite of expeditious development of safe and efficient drugs for such a contagious disease.
Nimisha, Patel +5 more
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Reproductive and Developmental Medicine, 2022 . Objective:. Altered bile acid transformation induces low-grade chronic inflammation and may play an important role in the pathophysiology of polycystic ovary syndrome (PCOS). Liquiritincan regulate bile acid metabolism and anti-inflammatory properties;
Zhi Li +6 more
doaj +1 more source
Liquiritin inhibits MRGPRX2-mediated pseudo-allergy through the PI3K/AKT and PLCγ signaling pathways
Heliyon, 2023 Liquiritin is a natural flavone with a variety of pharmacological effects derived from the medicinal food homology plant Glycyrrhiza uralensis Fisch. As a kind of lethal allergic reactions, pseudo-allergic reactions (PARs) arise from the Mas-related G ...
Lu Wang +5 more
doaj +1 more source
Liquiritin alleviates spinal cord injury through suppression of inflammation, oxidative stress, and cell apoptosis in a rat model [PDF]
, 2021 Purpose: Liquiritin is an extract from Glycyrrhiza Radix, one of the oldest traditional Chinese herbal medicines, which is commonly used to treat various injuries and swellings.
Luo, Yongsheng +5 more
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Liquiritin Alleviates Pain Through Inhibiting CXCL1/CXCR2 Signaling Pathway in Bone Cancer Pain Rat
Frontiers in Pharmacology, 2020 Bone cancer pain (BCP) is an intractable clinical problem, and lacked effective drugs for treating it. Recent research showed that several chemokines in the spinal cord are involved in the pathogenesis of BCP.
Huadong Ni +10 more
doaj +1 more source
Liquiritin Attenuates Pathological Cardiac Hypertrophy by Activating the PKA/LKB1/AMPK Pathway
Frontiers in Pharmacology, 2022 Background: Liquiritin (LQ) is one of the main flavonoids extracted from the roots of Glycyrrhiza spp., which are widely used in traditional Chinese medicine.
Xiahenazi Aiyasiding +16 more
doaj +1 more source
Differences in the endophytic fungal community and effective ingredients in root of three Glycyrrhiza species in Xinjiang, China [PDF]
PeerJ, 2021 Background Endophytic fungi influence the quality and quantity of the medicinal plant’s bioactive compounds through specific fungus-host interactions. Nevertheless, due to the paucity of information, the composition of endophytic fungal communities and ...
Hanli Dang +6 more
doaj +2 more sources
Protective effect of liquiritin on corticosterone-induced neurotoxicity in PC12 cells [PDF]
, 2019 Purpose: To determine the protective effects of liquiritin on corticosterone-induced neurotoxicity in rat pheochromocytoma (PC12) cells.Methods: Neurotoxicity in PC12 cells was induced by different concentrations of corticosterone.
Wu, Jing +4 more
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Frontiers in Pharmacology, 2021 Background: Stroke is the second leading cause of death in human life health, but current treatment strategies are limited to thrombolytic therapy, and because of the tight time window, many contraindications, and only a very small number of people can ...
Mengting Li +10 more
doaj +1 more source
, 2022 This study aimed to explore whether liquiritin affects the development of coronary heart disease by regulating the proliferation and migration of human vascular smooth muscle cells (hVSMCs).
Dajie Wang (11959011) +2 more
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