Results 61 to 70 of about 2,651 (189)

Image1_A novel Glycyrrhiza glabra extract liquiritin targeting NFATc1 activity and ROS levels to counteract ovariectomy-induced osteoporosis and bone loss in murine model.TIF [PDF]

, 2023
Osteoporosis, a prevalent osteolytic condition worldwide, necessitates effective strategies to inhibit excessive bone resorption by curbing osteoclast hyperactivation. Liquiritin (LIQ), an flavanone derivative employed in acute lung injury and rheumatoid
Zhenqiu Chen (7318289), Guoju Hong (7318286), Lin Zhou (141050), Guanqiang Zheng (17352808), Xiaoxia Zheng (2441932), Qiushi Wei (4631545), Wei He (131453)   +6 more
core   +1 more source

Formulation and Pharmacological Evaluation of a Medicine‐Food Homology Herb‐Based Formula for Sleep Enhancement

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
This outlines the progress for developing a sleep‐modulating herbal formula (SMF). It begins with the identification of effective compounds and quality control, then uses network pharmacology and molecular docking to explain the mechanisms behind the observation found on the behavioural and neurobiological results in animal study.
Jasmine U. Ting, Chunxue Zhao, Jia Xu, Chenrui Liu, Yungang Tian, Min Ye, Tao Cui, Jian Huang   +7 more
wiley   +1 more source

Liquiritin exhibits anti-acute lung injury activities through suppressing the JNK/Nur77/c-Jun pathway [PDF]

, 2023
Background Licorice (Glycyrrhiza uralensis Fisch.), a well-known traditional medicine, is traditionally used for the treatment of respiratory disorders, such as cough, sore throat, asthma and bronchitis.
Xuemei He, Shanhong Liu, Huihui Cao, Tangjia Yang, Jingyu Quan, Hongling Zhou, Yuyao Chen, Linzhong Yu, Junshan Liu, Zibin Lu, Kangtai Wu   +10 more
core   +1 more source

Glycyrrhiza uralensis Fisch. Root-associated microbiota: the multifaceted hubs associated with environmental factors, growth status and accumulation of secondary metabolites

Environmental Microbiome, 2022
Glycyrrhiza uralensis Fisch. is an important, perennial medicinal plant whose root microbiome is considered to play an important role in promoting accumulation of effective medicinal ingredients (liquiritin and glycrrhizic acid).
Chaoyun Chen, Chaofang Zhong, Xi Gao, Chongyang Tan, Hong Bai, Kang Ning   +5 more
doaj   +1 more source

Comprehensive Evaluation of Fructus Tsaoko, Seeds of Tsaoko Fructus and Ginger Made Seeds of Tsaoko Fructus Based on Drug‐Like Compounds and Aroma Analysis

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
This study mainly consists of two parts. First, after screening for drug‐like metabolites via LC–MS and GC–MS, a comprehensive evaluation model was established using a principal component analysis‐based weighted scoring method, by which the drug‐likeness ranking of three samples was determined.
Han Chen, Meiquan Yang, Weize Yang, Mingju Qi, Zongliang Xu, Tianmei Yang, Jinyu Zhang   +6 more
wiley   +1 more source

Deglycosylation of Liquiritin Strongly Enhances its Inhibitory Potential Towards UDP-Glucuronosyltransferase (UGT) Isoforms [PDF]

, 2013
The detailed mechanisms on licorice-drug interaction remain to be unclear. The aim of the present study is to investigate the inhibition of important UGT isoforms by two important ingredients of licorice, liquiritin, and liquiritigenin.
Guo, Bin, Yang, Lu, Fan, Xu-Ran, Hu, Cui-Min, Hong, Mo, Fang, Zhong-Ze, Zhang, Yan-Yan, He, Rong-Rong, Zhu, Xu, Sun, Xiao-Yu, Cao, Yun-Feng, Yang, Julin, Yu, Zhen-Wen   +12 more
core   +1 more source

Multi‐Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Amal Elrherabi, Oussama Khibech, Mohamed Bouhrim, Abdelouahid Laftouhi, Abdelaaty A. Shahat, Abdullah R. Alanzi, Rashed N. Herqash, Joe Miantezila Basilua, Mohamed Bnouham   +8 more
wiley   +1 more source

Liquiritin: A natural flavonoid with potential cardiovascular protection

Italian Journal of Food Science
Liquiritin is a flavonoid glycoside extracted from traditional Chinese medicine, Radix et Rhizoma Glycyrrhizae. The provided evidence has demonstrated that liquiritin is found beneficial in treating cardiovascular diseases. Inflammation and oxidation play key roles in cardiovascular diseases.
Lan Zhou, Jia-zhi Peng, Peng Zhou
openaire   +1 more source

Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy

Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley   +1 more source

Additional file 1 of Licorice extract inhibits growth of non-small cell lung cancer by down-regulating CDK4-Cyclin D1 complex and increasing CD8+ T cell infiltration [PDF]

, 2021
Additional file 1. Table S1 Candidate targets for each active compound. Fig. S1 Additional file 1  Inhibition of Liquiritin on H1975 cells. Fig. S2 Typical HPLC chromatogram of licorice extract where: (1) Liquiritin, 2.28% (2) Liquiritigenin, 0.18% (3 ...
Wei Xiao (16583), Ruijie Yang (11094735), Chao Huang (11555342), Jinglin Zhu (6089027), Chunli Zheng (716044), Yonghua Wang (138282), Jiangna Yan (11555339), Ruifei Huang (11555336), Yue Xiao (830802)   +8 more
core   +1 more source