Results 171 to 180 of about 2,127 (206)

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Using user-centered design to better understand challenges faced during genetic analyses by novice genomic researchers. [PDF]

Front Bioinform
Patel HV, Jarvik GP, Hall TO, Veenstra DL, Xie SJ, Crosslin DR.   +5 more
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

The effects of Chinese Buddhist meditation tradition: the impact of nature observation and literary creation. [PDF]

Front Psychol
Liang T, Sun M, Goto S.
europepmc   +1 more source

Heterogeneity of health anxiety in patients following rabies exposure: a latent profile analysis. [PDF]

Front Psychol
Ma Y, Xiong G, Xie H, Liang L, Mo C, Li H, Liu X.   +6 more
europepmc   +1 more source

Revolutionizing Thyroid Cancer Diagnosis: The Role of THADA-IGF2BP3 Fusions in Identifying Indolent Neoplasms.

J Cytol
Matia M, Kapatia G, Singh B, Gupta S, Sidana S.   +4 more
europepmc   +1 more source

Dendritic fibromyxolipoma of the male breast: case report and literary review. [PDF]

Front Med (Lausanne)
Li X, Wu D, Tian X, Xu T, Ge Q, Luo S, Wang J.   +6 more
europepmc   +1 more source

Development and Effectiveness of Humanities-Based Cognitive Behavior Therapy for Adolescents With Problematic Gaming Behavior. [PDF]

Psychiatry Investig
Park Y, Choi JA, Han DH.
europepmc   +1 more source

Shared reading as an intervention to improve health and well-being in adults: a scoping review. [PDF]

Front Psychol
Järvholm K, Ohlsson A, Bernhardsson K, Gustafsson AW, Johnsson P, Malmström M, Wistrand J, Forslid T.   +7 more
europepmc   +1 more source

Enhancing ethical self-efficacy among dementia caregiver staff: A mixed-methods feasibility study of the care programme. [PDF]

Int J Nurs Stud Adv
Lauridsen S, Skov SS, Thorup LM, Berg ME, Folker AP, Simonsen P, Schou-Juul F.   +6 more
europepmc   +1 more source