Results 101 to 110 of about 5,208,749 (290)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Examining language attitudes and use: A survey of Indonesian university students’ loyalty to their ethnic languages

open access: yesIndonesian Journal of Applied Linguistics
Currently, a large number of ethnic languages worldwide are losing their vitality and popularity due to globalization and the influence of dominant languages such as English and Indonesian.
Dingding Haerudin   +3 more
doaj   +1 more source

Further education learners' prior experience of career education and guidance: A case study of Chesterfield College. [PDF]

open access: yes, 2015
This article explores further education (FE) students' prior experiences of careers education. The research draws on and extends the limited literature that exists around career support in further education. A mixed methods case study was used to explore
Hooley, Tristram, Woolly, Amy
core   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Academic literacies twenty years on: a community-sourced literature review [PDF]

open access: yes, 2019
In 1998, the paper ‘Student writing in higher education: an academic literacies approach’ by Mary Lea and Brian Street reinvigorated debate concerning ‘what it means to be academically literate’ (1998, p.158).
Hilsdon, John   +2 more
core   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

AN ANALYSIS OF POLITICAL EDUCATION IN THE “THE THIRTY-NINE STEPS” NOVEL BY JOHN BUCHAN [PDF]

open access: yes, 2005
Literature is a work that gives much contribution to provide knowledge and pleasure. Short story, poem, play, and novel are part of literature. Novel is a long fiction that tells a life-like story about any kinds of life.
YULIARSIH, SRI
core  

Understanding the development of teaching and learning resources: A review [PDF]

open access: yes, 2002
This paper is a literature review of research concerned with the production of learning resources in higher education (HE).
Issroff, Kim, Plewes, Louise
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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