Results 81 to 90 of about 5,208,749 (290)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Professional knowledge in initial teacher education (ITE): a preliminary review of Hispanic literature [PDF]

open access: yes, 2007
The global dominance of English as the principal language of international interchange in the teacher education field has, perhaps, diverted English-speaking scholars from the task of reviewing discourses in non-English languages. Taking as its focus the
McCluskey, Raymond
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Effect of Motivational Highlight DVDs on State Self-Confidence in Elite Female Hockey Players [PDF]

open access: yes, 2007
Formal coach education programmes, driven by the national governing bodies of individual sports, have for many years been regarded as essential in the development of competent, qualified coaches.
Dicks, P.   +4 more
core   +5 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Robin Hood möter Donald Trump: Textuniversumbaserat litteraturarbete på mellanstadiet

open access: yesNordic Journal of Literacy Research
Denna studie undersöker hur textuniversumbaserad undervisning kan påverka mellanstadieelevers möjligheter att förstå, tolka och omskapa skönlitterära texter.
Anna-Maija Norberg   +2 more
doaj   +1 more source

Development and Social Justice: Education, Training and Health in Sudan [PDF]

open access: yes, 2013
This paper discusses the importance of sound policies for achieving social development and social justice in provision of education, training and health services in Sudan. Different from Sudanese literature, we provide new contributions by explaining the
Samia Satti Osman Mohamed Nour
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Engineering Education Periodicals and Proceedings: Increasing Awareness of and Access to the Literature [PDF]

open access: yes, 2002
In the vast realm, of engineering literature there is a set of publications that is often unknown and certainly underutilized: engineering education periodicals and proceedings.
De Petro, Thomas G
core  

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