Results 81 to 90 of about 1,657,475 (313)

Language-Literature Integration in High-School EFL Education: Investigating Students' Perspectives [PDF]

open access: yes, 2020
The use of literature in English as a Foreign Language (EFL) environments has had a long and controversial history. Currently, literature has returned to the language classroom once similarities between literary texts and everyday communication have ...
Zyngier, Sonia, Viana, Vander
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Growing great teachers: review of literature [PDF]

open access: yes, 2013
Introduction: This review of literature is intended to make a contribution to the Growing Great Teachers project in several ways, each of which is a normal expectation for a review of literature in research and evaluation.

core  

Children's literature in education

open access: yes, 2017
Children’s literature is a dynamic entity in its own right that offers its readers many avenues for pleasure, reflection and emotional engagement. As this essay argues, its place in education was established centuries ago, but this association continues ...
Mallan, Kerry M., Kerry Mallan
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A Literature Review of Educational Robotics and Early Childhood Education

open access: yes, 2023
Educational robotics is an emerging field with school aged children; however, it is relatively new to the field of early childhood education and care.
Keane, T, Garvis, S
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Gamification of Education: A Review of Literature

open access: yes, 2014
We synthesized the literature on gamification of education by conducting a review of the literature on gamification in the educational and learning context. Based on our review, we identified several game design elements that are used in education. These game design elements include points, levels/stages, badges, leaderboards, prizes, progress bars ...
Fiona Fui-Hoon Nah   +4 more
openaire   +2 more sources

The Weber health education model : health care provider-patient interactions [PDF]

open access: yes, 2004
ix, 128 leaves ; 29 cm. --This qualitative project introduces and explores the creation of a new health education model, which emerged from a personal narrative inquiry. Using research literature and studying four patient interactions through narrative
University of Lethbridge. Faculty of Education   +1 more
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