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Transcription-Driven Repurposing of Cardiotonic Steroids for Lithium Treatment of Severe Depression [PDF]

open access: yesCells
Lithium is prescribed as a mood stabilizer for bipolar disorder and severe depression. However, the mechanism of action of lithium is unknown and there are major side effects associated with prolonged medication.
Richard Killick   +7 more
doaj   +3 more sources

Lithium prescribing during pregnancy: a UK primary care database study. [PDF]

open access: yesPLoS ONE, 2015
BackgroundWomen taking lithium must decide whether to continue the medication if they conceive or plan to conceive. Little is known about the extent of prescribing of lithium during pregnancy.AimsTo determine: 1) the prevalence of lithium prescribing ...
Rachel L McCrea   +6 more
doaj   +3 more sources

Parkinson’s Disease: Potential Actions of Lithium by Targeting the WNT/β-Catenin Pathway, Oxidative Stress, Inflammation and Glutamatergic Pathway

open access: yesCells, 2021
Parkinson’s disease (PD) is one of the major neurodegenerative diseases (ND) which presents a progressive neurodegeneration characterized by loss of dopamine in the substantia nigra pars compacta.
Alexandre Vallée   +2 more
doaj   +2 more sources

Bipolar disorder and medication: adherence, patients' knowledge and serum monitoring of lithium carbonate [PDF]

open access: diamondRevista Latino-Americana de Enfermagem, 2013
OBJECTIVES this study featured patients with affective bipolar disorder who were making use of lithium and received care at an outpatient care center located in a country town in the state of Sao Paulo in 2009; it assessed the adherence and knowledge of ...
Camila de Souza   +3 more
openalex   +2 more sources

Challenging the Safety Threshold: Neurotoxicity in Bipolar Disorder Treatment with Lithium at Therapeutic Serum Levels [PDF]

open access: yesPsychiatry and Clinical Psychopharmacology
Bipolar disorder is a complex mental disorder that often requires long-term medication management. Lithium carbonate is widely used to prevent and treat the recurrence of bipolar disorder.
Jinbo Chen   +7 more
doaj   +2 more sources

Lithium: a potential therapeutic strategy in obsessive–compulsive disorder by targeting the canonical WNT/β pathway

open access: yesTranslational Psychiatry, 2021
Obsessive–compulsive disorder (OCD) is a neuropsychiatric disorder characterized b–y recurrent and distinctive obsessions and/or compulsions. The etiologies remain unclear.
Alexandre Vallée   +2 more
doaj   +2 more sources

Lithium Toxicity in the Setting of Nonsteroidal Anti-Inflammatory Medications [PDF]

open access: goldCase Reports in Nephrology, 2013
Lithium toxicity is known to affect multiple organ systems, including the central nervous system. Lithium levels have been used in the diagnosis of toxicity and in assessing response to management. There is evidence that nonsteroidal anti-inflammatory medications (NSAIDs) can increase lithium levels and decrease renal lithium clearance.
Syed Adeel Hassan   +3 more
openalex   +4 more sources

Differential acute impact of therapeutically effective and overdose concentrations of lithium on human neuronal single cell and network function

open access: yesTranslational Psychiatry, 2021
Lithium salts are used as mood-balancing medication prescribed to patients suffering from neuropsychiatric disorders, such as bipolar disorder and major depressive disorder.
Julia Izsak   +8 more
doaj   +2 more sources

Short-term and long-term effects of Muslim fasting on lithium pharmacokinetics and renal function in bipolar disorder: a prospective observational study [PDF]

open access: yesInternational Journal of Bipolar Disorders
This prospective observational study aimed to investigate the effects of Ramadan fasting on serum lithium levels, renal function, and electrolyte balance in patients with bipolar disorder undergoing lithium maintenance therapy. Conducted in Saudi Arabia,
Mohamed Abouzed   +8 more
doaj   +2 more sources

Co-prescription of medication for bipolar disorder and diabetes mellitus: a nationwide population-based study with focus on gender differences [PDF]

open access: yesBMC Medicine, 2012
Background Studies have shown a correlation between bipolar disorder and diabetes mellitus. It is unclear if this correlation is a part of common pathophysiological pathways, or if medication for bipolar disorder has negative effects on blood sugar ...
Svendal Gjertrud   +4 more
doaj   +5 more sources

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