The efficacy of the benzimidazoles oxfendazole and flubendazole against Litomosoides sigmodontis is dependent on the adaptive and innate immune system [PDF]
Frontiers in Microbiology, 2023 Filarial nematodes can cause debilitating diseases such as lymphatic filariasis and onchocerciasis. Oxfendazole (OXF) is one promising macrofilaricidal candidate with improved oral availability compared to flubendazole (FBZ), and OXF is currently under ...
Frederic Risch +14 more
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ILC2s Control Microfilaremia During Litomosoides sigmodontis Infection in Rag2-/- Mice [PDF]
Frontiers in Immunology, 2022 Group 2 innate lymphoid cells (ILC2s) are inducers of type 2 immune responses, but their role during filarial infection remains unclear. In the present study, we used the Litomosoides sigmodontis rodent model of filariasis to analyze ILC2s during ...
Julia J. Reichwald +13 more
doaj +3 more sources
The infective larva of Litomosoides yutajensis Guerrero et al., 2003 (Nematoda: Onchocercidae), a Wolbachia-free filaria from bat [PDF]
Parasite, 2006 The infective larva of Litomosoides yutajensis Guerrero et al., 2003, a parasite of the bat Pteronotus parnellii, is described; it is distinct from congeneric infective larvae by the absence of caudal lappets.
Guerrero R. +3 more
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Identification and ultrastructural characterization of the Wolbachia symbiont in Litomosoides chagasfilhoi [PDF]
Parasites & Vectors, 2015 Background Filarial nematodes are arthropod-transmitted parasites of vertebrates that affect more than 150 million people around the world and remain a major public health problem throughout tropical and subtropical regions.
Vanessa Aparecida Chagas-Moutinho +3 more
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International Journal for Parasitology: Drugs and Drug Resistance, 2020 The quinazolines CBR417 and CBR490 were previously shown to be potent anti-wolbachials that deplete Wolbachia endosymbionts of filarial nematodes and present promising pre-clinical candidates for human filarial diseases such as onchocerciasis.
Marc P. Hübner +24 more
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Litomosoides brasiliensis (Nematoda: Onchocercidae) infecting chiropterans in the Legal Amazon region, Brazil [PDF]
Revista Brasileira de Parasitologia Veterinária, 2022 Chiropterans play an important role in the maintenance of the environmental balance, since they are pollinators, seed dispersers and predators. They contribute to transmission and spreading of microorganisms such as helminths, fungi, protozoa, bacteria ...
Thaliane França Costa +8 more
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Development of patent Litomosoides sigmodontis infections in semi-susceptible C57BL/6 mice in the absence of adaptive immune responses [PDF]
Parasites & Vectors, 2015 Background One of the most advantageous research aspects of the murine model of filariasis, Litomosoides sigmodontis, is the availability of mouse strains with varying susceptibility to the nematode infection. In C57BL/6 mice, L.
Laura E. Layland +5 more
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Infecção natural do Holochilus brasiliensis nanus Thomas, 1897 (Rodentia, cricetidae) por Litomosoides carinii Natural infection of Holochilius brasiliensis nanus Thomas, 1897 (Rodentia, Cricetidae) by Litomosoides carinii [PDF]
Memorias do Instituto Oswaldo Cruz, 1985 É registrada a infecção natural do Holochilus brasiliensis nanus, um pequeno roedor semi-aquático da Baixada Ocidental do Estado do Maranhão, Brasil, por Litomosoides carinii.It is recorded the natural infection of Holochilus brasiliensis nanus, a small ...
J. C. Holanda +3 more
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Limited role of mast cells during infection with the parasitic nematode Litomosoides sigmodontis.
PLoS Neglected Tropical Diseases, 2020 Mast cells are innate effector cells that due to their localization in the tissue form the first line of defense against parasites. We have previously shown that specifically mucosal mast cells were essential for the termination of the intestinal ...
Lara Christine Linnemann +4 more
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Revista Mexicana de Biodiversidad, 2015 Litomosoides pardinasi es registrada por primera vez en roedores nativos y exóticos de Chile. La especieLitomosoides pardinasi, parásita de Phyllotis xanthopygus y Oligoryzomys longicaudatus en la Patagonia Argentina,fue encontrada en Chile parasitando ...
Carlos Landaeta-Aqueveque +7 more
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