Does litomosoides sigmodontis synthesize dimethylethanolamine from choline? [PDF]
Parasitology, 2008 Juvenile female Litomosoides sigmodontis secrete a protein (Juv-p120) highly modified with dimethylethanolamine (DMAE). In an attempt to establish the source of this decoration worms were pulsed with [3H]-choline and [3H]-ethanolamine and the radio ...
Allen, J E +4 more
core +7 more sources
A Combination of Deworming and Prime-Boost Vaccination Regimen Restores Efficacy of Vaccination Against Influenza in Helminth-Infected Mice [PDF]
Frontiers in Immunology, 2021 Helminths still infect a quarter of the human population. They manage to establish chronic infections by downmodulating the immune system of their hosts.
Nadine Stetter +7 more
doaj +2 more sources
Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis [PDF]
Vaccines, 2023 More than two-hundred-million people are infected with filariae worldwide. However, there is no vaccine available that confers long-lasting protection against filarial infections.
Johanna F. Scheunemann +15 more
doaj +2 more sources
A vascular filarial nematode in sika deer (Cervus nippon): Morphological and molecular characterization of Elaeophora (Nematoda: Onchocercidae) in Japan [PDF]
International Journal for Parasitology: Parasites and WildlifeElaeophora (Nematoda: Onchocercidae), a filarial nematode infecting the blood vessels of ruminants and horses, is transmitted by tabanid flies. Elaeophora elaphi was previously detected in wild sika deer in Wakayama Prefecture, Japan in 2009; however ...
Toshihiro Tokiwa +10 more
doaj +2 more sources
The genome of Litomosoides sigmodontis illuminates the origins of Y chromosomes in filarial nematodes. [PDF]
PLoS GeneticsHeteromorphic sex chromosomes are usually thought to have originated from a pair of autosomes that acquired a sex-determining locus and subsequently stopped recombining, leading to degeneration of the sex-limited chromosome.
Lewis Stevens +6 more
doaj +2 more sources
Comparison of the macrofilaricidal efficacy of oxfendazole and its isomers against the rodent filaria Litomosoides sigmodontis [PDF]
Parasitology, 2022 In this study with the filarial modelLitomosoides sigmodontis, we demonstrate that the worms ingest host red blood cells at a precise moment of their life-cycle, immediately after the fourth moult. The red blood cells (RBC) were identified microscopically in live worms immobilized in PBS at 4 °C, and their density assessed.
Frederic Risch +6 more
openalex +6 more sources
Host environment shapes filarial parasite fitness and Wolbachia endosymbionts dynamics. [PDF]
PLoS PathogensFilarial nematodes, responsible for diseases like lymphatic filariasis and onchocerciasis, depend on symbiotic Wolbachia bacteria for reproduction and development.
Frédéric Fercoq +11 more
doaj +2 more sources
Caldasia, 1999 A key is provided for the identification of eight species of microfilariae of Litomosoides (Filarioidea: Onchocercidae) found in the blood of 85 Colombian bats. Eleven new host records for Colombia are reported for L. brasiliensis, L.
Marinkelle Cornelis J. +1 more
doaj +2 more sources
Eosinophils Are an Endogenous Source of Interleukin-4 during Filarial Infections and Contribute to the Development of an Optimal T Helper 2 Response [PDF]
Journal of Innate ImmunityIntroduction: Interleukin-4 (IL-4) is a central regulator of type 2 immunity, crucial for the defense against multicellular parasites like helminths. This study focuses on its roles and cellular sources during Litomosoides sigmodontis infection, a model ...
Cécile Guth +10 more
doaj +2 more sources
Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during Litomosoides sigmodontis filarial infection. [PDF]
Front Immunol, 2022 Remion E +9 more
europepmc +2 more sources