Results 111 to 120 of about 1,768,893 (247)

Vaccine effectiveness of live attenuated and trivalent inactivated influenza vaccination in 2010/11 to 2015/16: the SIVE II record linkage study

Health Technology Assessment, 2020
Background: There is good evidence of vaccine effectiveness in healthy individuals but less robust evidence for vaccine effectiveness in the populations targeted for influenza vaccination.
Colin R Simpson, Nazir I Lone, Kim Kavanagh, Tanya Englishby, Chris Robertson, Jim McMenamin, Beatrix von Wissman, Eleftheria Vasileiou, Christopher C Butler, Lewis D Ritchie, Rory Gunson, Jürgen Schwarze, Aziz Sheikh   +12 more
doaj   +1 more source

Merger Efficiency and Coordinated Effects: Nothing to Sneeze at? Evidence From Cough and Cold Medicines in the Philippines

Southern Economic Journal, EarlyView.
ABSTRACT We investigate the competitive effects of a merger in the cough and cold medicines segment between GlaxoSmithKline (GSK) and Pfizer. The parties offered efficiency gains, and authorities concluded the merger would not lessen competition. Using product‐level data from the Philippines, we estimate a structural demand model to assess efficiency ...
Farasat A. S. Bokhari, Sean Ennis, Carlos Vega, Weijie Yan   +3 more
wiley   +1 more source

Stalking influenza by vaccination with pre-fusion headless HA mini-stem. [PDF]

, 2016
Inaccuracies in prediction of circulating viral strain genotypes and the possibility of novel reassortants causing a pandemic outbreak necessitate the development of an anti-influenza vaccine with increased breadth of protection and potential for rapid ...
Carnell, George, Temperton, Nigel J., Mallajosyula, VVA, Poon, Leo LM, Mallajosyula, V Vamsee Aditya, Temperton, N, Poon, LLM, Chin, Alex WH, Mallajosyula, VV, Chin, Alex W H, Carnell, G, Valkenburg, Sophie A, Li, OTW, Poon, Leo L M, Chin, WH, Mallajosyula, Vamsee Aditya V, Poon, LML, Li, Olive T W, Varadarajan, Raghavan, Doak, SA, Li, Olive TW, Temperton, Nigel, Chin, AWH, Valkenburg, SA, Varadarajan, R   +24 more
core   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

DEVELOPMENT OF PROTOTYPE OF UNIVERSAL INFLUENZA VACCINE BASED ON LIVE ATTENUATED INFLUENZA VACCINE VIRAL VECTOR

Инфекция и иммунитет, 2018
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D. A. Mezhenskaia, T. S. Кotomina, I. N. Isakova-Sivak, V. A. Matyushenko, A. S. Evsina, M. C. Kim, S. M. Kang, L. G. Rudenko   +7 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Evidence and guidance on vaccine safety and effectiveness in subpopulations [PDF]

, 2011
This dissertation examines post-licensing vaccine safety and effectiveness against two major respiratory diseases in specific subpopulations, with emphasis on safety.
Mak, Tippi
core   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source

Development of an influenza virus vaccine using the baculovirus-insect cell expression system : implications for pandemic preparedness [PDF]

, 2009
Key word Influenza, rHA, vaccine, baculovirus, insect cells, production, pandemic preparedness Influenza (or flu) is a highly contagious, acute viral respiratory disease that occurs seasonally in most parts of the world and is caused by influenza ...
Cox, M.M.J.
core