Results 151 to 160 of about 1,768,893 (247)

Dual Antiviral and Immunomodulatory Effects of Phytochemicals in Influenza A Virus Infection: Targeting Key Host Signaling Pathways

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Influenza A virus modulates host innate immune pathways, including TLR, RIG‐I, MAPK, and NF‐κB signaling, to support replication and drive inflammatory pathology. Plant‐derived phytocompounds target these interconnected pathways, offering a potential host‐directed immunomodulatory approach complementary to conventional antivirals.
Dibakar Chowdhury   +3 more
wiley   +1 more source

Past and Present Vaccinations in Sweden

open access: yes
Acta Paediatrica, Volume 115, Issue 11, Page 2505-2510, November 2026.
Sven Arne Silfverdal
wiley   +1 more source

Cholesterol 25‐Hydroxylase Deficiency Provides an Optimal and Durable Protective T Helper 1 Immunity via Interleukin‐12–Interleukin‐2 Axis in BCG‐Vaccinated Mice

open access: yesMedComm, Volume 7, Issue 10, October 2026.
CH25H deficiency permits optimal dendritic cell activation following BCG exposure, characterized by increased IL‐12p70 production. In vivo, CH25H deficiency promotes enhanced BCG‐mediated protection and sustained IL‐2 producing T cell response. ABSTRACT Bacillus Calmette‐Guérin (BCG) remains the only licensed vaccine for tuberculosis (TB), yet its ...
Hagyu Kim   +6 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao   +5 more
wiley   +1 more source

Influenza vaccine : what you need to know : (flu vaccine, live, intranasal) 2014-2015 [PDF]

open access: yes
Vaccine Information Statement (Interim)Live Attenuated Influenza Vaccine1. Why get vaccinated? -- 2. Live, attenuated flu vaccine-LAIV, Nasal Spray \u2013 3. Some people should not get this vaccine \u2013 4. Risks of a vaccine reaction \u2013 5.

core  

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

open access: yesSmall, Volume 22, Issue 55, 1 October 2026.
Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini   +3 more
wiley   +1 more source

uPAR‐Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non‐Human Primates With Serum Aminotransferase Activity as a Safety Monitor

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
GFD‐CD3, a uPAR‐targeting T‐cell engager, effectively cleared senescent cells and mitigated age‐related pathologies with a favorable safety profile under transaminase‐guided monitoring. ABSTRACT Senolytic CAR‐T cells targeting uPAR induce dose‐dependent toxicities.
Jian Deng   +13 more
wiley   +1 more source

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