Results 251 to 260 of about 43,630 (288)

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

The Sleep Opportunity, Need and Ability (SONA) Theory

Journal of Sleep Research, EarlyView.
ABSTRACT ‘How much sleep does one need?’ is a critical question that has been difficult to answer. The long history of sleep research has culminated in population‐derived normative values of 7 to 9 h of sleep per night to avoid dysfunction. Such a wide range is sufficiently large that one cannot know what is required for any given individual.
Hannah Scott, Michael Perlis
wiley   +1 more source

Moderate to Severe Obstructive Sleep Apnea Is a Risk Factor for Severe COVID‐19—A Nationwide Cohort Study

Journal of Sleep Research, EarlyView.
ABSTRACT The impact of obstructive sleep apnea (OSA) and positive airway pressure (PAP) treatment on COVID‐19 severity is unclear. In this population‐based, nationwide study using multi‐register data, we aimed to assess if OSA is a risk factor for COVID‐19 severity and how adherence to PAP treatment and clinical characteristics affect the risk. Swedish
Mirjam Ljunggren, Andreas Palm, Magnus Ekström, Josefin Sundh, Ludger Grote, Huiqi Li, Fredrik Nyberg, Össur Ingi Emilsson   +7 more
wiley   +1 more source

From leprosy to ground zero: Imagining futures in a world of elimination

Medical Anthropology Quarterly, EarlyView.
Abstract Achieving a target of zero—zero disease, zero disability, and zero discrimination—has become the dominant focus of campaigns to control or eliminate diseases, from HIV/AIDS to malaria to leprosy. Given the historical failure of most eradication programs over the last century, such teleological imaginings of disease‐free futures might seem ...
James Staples
wiley   +1 more source

‘Breastfeeding Is Not the Sole Responsibility of Women’: A Qualitative Examination of the Supportive Environment for Breastfeeding in Nigeria Across Levels of the Socioecological Model

Maternal &Child Nutrition, EarlyView.
Prior efforts to understand the determinants of breastfeeding have heavily focused on women themselves. This qualitative analysis identified key facilitators and barriers to strengthening the supportive environment for optimal breastfeeding practices in Nigeria.
Elizabeth Costenbader, Mackenzie Green, Kate Litvin, Christina Memmott, Tochukwu Osuji, Izuchukwu Offiaeli, Nemat Hajeebhoy   +6 more
wiley   +1 more source

Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology

Annals of the New York Academy of Sciences, EarlyView.
Bats are recognized to have distinct immune systems from other vertebrates that may allow them to host virulent pathogens without showing disease. However, these flying mammals are also incredibly diverse, such that bats should not be expected to be immunologically homogenous.
Daniel J. Becker, Amanda Vicente‐Santos, Ashley B. Reers, B. R. Ansil, Mika O'Shea, Caroline A. Cummings, Alicia J. Roistacher, Rita M. Quintela‐Tizon, Manuela M. T. Pereira, Juniper Rosen, Arinjay Banerjee, Hannah K. Frank   +11 more
wiley   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

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Influenza Vaccination with a Live Attenuated Vaccine

AJN, American Journal of Nursing, 2009
Influenza is a highly contagious, acute respiratory illness with a long history of outbreaks dating back several centuries. Although immunization is an effective means of protection against influenza, vaccination rates have been suboptimal, especially among certain high-risk groups, including children and health care personnel.
Elizabeth Helm, Jay Bauman, Frank J. Malinoski, Brigit Van Graafeiland, Michele Michael   +4 more
openaire   +3 more sources

LIVE ATTENUATED VARICELLA VACCINE

Annual Review of Microbiology, 1996
Varicella-zoster virus (VZV) is a ubiquitous human pathogen that causes varicella, commonly called chicken pox; establishes latency; and reactivates as herpes zoster, referred to as shingles. A live attenuated varicella vaccine, derived from the Oka strain of VZV has clinical efficacy for the prevention of varicella.
Ann M. Arvin, Anne A. Gershon
openaire   +3 more sources

Attenuation Methods for Live Vaccines

2020
Vaccination was developed by Edward Jenner in 1796. Since then, vaccination and vaccine development research has been a hotspot of research in the scientific community. Various ways of vaccine development are successfully employed in mass production of vaccines. One of the most successful ways to generate vaccines is the method of virulence attenuation
Dipasree Hajra, Akshay Datey, Dipshikha Chakravortty   +2 more
openaire   +3 more sources