Results 251 to 260 of about 91,730 (350)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

An Overview of Current Knowledge on in vitro Babesia Cultivation for Production of Live Attenuated Vaccines for Bovine Babesiosis in Mexico. [PDF]

Front Vet Sci, 2020
Alvarez JA, Rojas C, Figueroa JV.
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Vaccination With Live Attenuated Vaccines in Four Children With Chronic Myeloid Leukemia While on Imatinib Treatment. [PDF]

Front Immunol, 2020
Bettoni da Cunha-Riehm C, Hildebrand V, Nathrath M, Metzler M, Suttorp M.   +4 more
europepmc   +1 more source

Author response: A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus

, 2020
Elsio A. Wunder, Haritha Adhikarla, Camila Hamond, Katharine A. Owers, Li Liang, Camila B. Rodrigues, Vimla Bisht, Jarlath E. Nally, David P. Alt, Mitermayer Galvão dos Reis, Peter J. Diggle, Philip L. Felgner, Albert I. Ko   +12 more
openalex   +1 more source

Live Attenuated Vaccine With a Stabilized Mutation and Gene Deletion for Prevention of Respiratory Syncytial Virus Disease in Young Children [PDF]

, 2019
Michael N. Teng, Asunción Mejías, Octavio Ramilo, Mark E. Peeples   +3 more
openalex   +1 more source

Post‐COVID‐19 Pandemic Growth of National Hearing Aid Utilisation: A Population‐Based Study

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Hearing loss affects 538 million people globally. Untreated hearing loss may be compensated through speech reading. The COVID‐19 pandemic prompted face coverings, causing communication challenges. We aim to investigate the possible impact of the COVID‐19 outbreak era on hearing aid demand. Study Design Ecological time‐series study.
Keren Oren, Itai Hazan, Stave Edri Abikasis, Tomer Kerman, Liron Kariv, Oded Cohen, Oren Ziv   +6 more
wiley   +1 more source

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

European Journal of Clinical Investigation, EarlyView.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

European Journal of Haematology, EarlyView.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot, Frederic Baleydier, Laure Pittet, Geraldine Blanchard‐Rohner   +3 more
wiley   +1 more source

Comparison of Immunogenicity and Protective Efficacy of PPR Live Attenuated Vaccines (Nigeria 75/1 and Sungri 96) Administered by Intranasal and Subcutaneous Routes. [PDF]

Vaccines (Basel), 2020
Mahapatra M, Selvaraj M, Parida S.
europepmc   +1 more source