Results 41 to 50 of about 41,266 (261)

Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame. [PDF]

, 2015
The polio eradication endgame aims to bring transmission of all polioviruses to a halt. To achieve this aim, it is essential to block viral replication in individuals via induction of a robust mucosal immune response. Although it has long been recognized
Anis E, Davis DC, Edward PK Parker, Ghendon YZ, Glezen WP, Glezen WP, Herremans MM, Herremans TM, Hovi T, Kathleen M O’Reilly, Margarita Pons-Salort, Marine WM, Natalie A Molodecky, Nicholas C Grassly, Ogra PL, Wehrle PF, WHO Collaborative Study Group on Oral and Inactivated Poliovirus Vaccines   +16 more
core   +3 more sources

Live-attenuated vaccination in patients with inflammatory bowel disease while continuing or after elective switch to vedolizumab [PDF]

Intestinal Research
Background/Aims Vedolizumab (VDZ) is a gut-selective agent with a favorable safety profile. We aimed to assess the feasibility of elective switch from other advanced therapies to VDZ and subsequent live-attenuated vaccination while continuing VDZ in ...
Hisashi Shiga, Hiroshi Nagai, Yusuke Shimoyama, Takeo Naito, Rintaro Moroi, Yoichi Kakuta, Yoshitaka Kinouchi, Atsushi Masamune   +7 more
doaj   +1 more source

Evaluation of the Delivery of a Live Attenuated Porcine Reproductive and Respiratory Syndrome Virus as a Unit Solid Dose Injectable Vaccine

Vaccines, 2022
Solid dose vaccine formulation and delivery systems offer potential advantages over traditional liquid vaccine formulations. In addition to enhanced thermostability, needle-free delivery of unit solid dose injectable (USDI) vaccines offers safe, rapid ...
Ellie Hayhurst, Emily Rose, Miriam Pedrera, Jane C. Edwards, Natalia Kotynska, Daisy Grainger, Yashar Sadigh, John Flannery, Ludo Bonnet, Ritwik Ritwik, Pawan Dulal, M. Keith Howard, Simon P. Graham   +12 more
doaj   +1 more source

Natural Attenuated Vaccines for Pasteurella multocida

Biology
Pasteurella multocida is capable of infecting various animal species, causing hemorrhagic septicemia or infectious pneumonia, and it is widely prevalent and pathogenic worldwide.
Qingyuan Xu, Lijun Guan, Yun Xue, Zhanqin Zhao   +3 more
doaj   +1 more source

Post vaccinal temporary sensorineural hearing loss [PDF]

, 2018
In our systematic research we identified four studies concerning the onset of neurological adverse events following vaccination and two excluding this association.
De Cesare, Donato Pompeo, De Marco, Federica, Di Folco, Francesco, Di Luca, Natale Mario, Massoni, Francesco, Ricci, Serafino, Sacco, Carmina, Tomei, Francesco, Tomei, Gianfranco   +8 more
core   +1 more source

Roadblocks to translational challenges on viral pathogenesis. [PDF]

, 2013
Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven, Drosten, Christian, Picker, Louis, Subbarao, Kanta, Suzich, Joann   +4 more
core   +1 more source

Single-Dose Immunogenic DNA Vaccines Coding for Live-Attenuated Alpha- and Flaviviruses

Viruses
Single-dose, immunogenic DNA (iDNA) vaccines coding for whole live-attenuated viruses are reviewed. This platform, sometimes called immunization DNA, has been used for vaccine development for flavi- and alphaviruses.
Peter Pushko, Igor S. Lukashevich, Dylan M. Johnson, Irina Tretyakova   +3 more
doaj   +1 more source

Systems Vaccinology for a Live Attenuated Tularemia Vaccine Reveals Unique Transcriptional Signatures That Predict Humoral and Cellular Immune Responses

Vaccines, 2019
Background: Tularemia is a potential biological weapon due to its high infectivity and ease of dissemination. This study aimed to characterize the innate and adaptive responses induced by two different lots of a live attenuated tularemia vaccine and ...
Muktha S. Natrajan, Nadine Rouphael, Lilin Lai, Dmitri Kazmin, Travis L. Jensen, David S. Weiss, Chris Ibegbu, Marcelo B. Sztein, William F. Hooper, Heather Hill, Evan J. Anderson, Robert Johnson, Patrick Sanz, Bali Pulendran, Johannes B. Goll, Mark J. Mulligan   +15 more
doaj   +1 more source

Live-attenuatedShigellavaccines

Expert Review of Vaccines, 2006
Several live-attenuated Shigella vaccines, with well-defined mutations in specific genes, have shown great promise in eliciting significant immune responses when given orally to volunteers. These responses have been measured by evaluating antibody-secreting cells, serum antibody levels and fecal immunoglobulin A to bacterial lipopolysaccharide and to ...
Malabi M, Venkatesan, Ryan T, Ranallo
openaire   +2 more sources

Elegant and Innovative Recoding Strategies for Advancing Vaccine Development

Vaccines
Recoding strategies have emerged as a promising approach for developing safer and more effective vaccines by altering the genetic structure of microorganisms, such as viruses, without changing their proteins.
François Meurens, Fanny Renois, Uladzimir Karniychuk   +2 more
doaj   +1 more source