Results 51 to 60 of about 99,732 (351)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Research note: Comparison of live attenuated and non-attenuated Eimeria vaccines on safety following overdose administration using the European pharmacopoeia monograph model

open access: yesPoultry Science
Live non-attenuated and attenuated coccidiosis vaccines are available and induce a solid immune response to Eimeria spp. However, knowledge regarding the safety of live non-attenuated Eimeria vaccines is still limited.
Marc Pagès   +5 more
doaj   +1 more source

Development of an experimental inactivated PRRSV vaccine that induces virus-neutralizing antibodies [PDF]

open access: yes, 2009
Porcine reproductive and respiratory syndrome virus (PRRSV) can induce reproductive disorders and is involved in the porcine respiratory disease complex, causing tremendous economic losses to the swine industry.
Delputte, Peter   +4 more
core   +3 more sources

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Assessment of mycoplasma vaccine efficacy in reducing infection with Newcastle disease virus

open access: yesVacciMonitor, 2023
The present work recorded the impact of using Mycoplasma gallisepticum vaccines on post-vaccinal response and protection against challenge with Newcastle disease virus. Specific pathogen-free chickens were divided into eight groups of forty chickens each.
Hala Mahmoud   +4 more
doaj  

Novel Vaccine Technologies in Veterinary Medicine: A Herald to Human Medicine Vaccines

open access: yesFrontiers in Veterinary Science, 2021
The success of inactivated and live-attenuated vaccines has enhanced livestock productivity, promoted food security, and attenuated the morbidity and mortality of several human, animal, and zoonotic diseases.
Virginia Aida   +14 more
doaj   +1 more source

Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]

open access: yes, 2011
Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Antonis, A.F.G.   +3 more
core   +2 more sources

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham   +11 more
wiley   +1 more source

Developing live vaccines against plague

open access: yesJournal of Infection in Developing Countries, 2011
Three great plague pandemics caused by the gram-negative bacterium Yersinia pestis have killed nearly 200 million people and it has been linked to biowarfare in the past. Plague is endemic in many parts of the world.
Wei Sun   +2 more
doaj   +1 more source

Coinfection in the host can result in functional complementation between live vaccines and virulent virus

open access: yesVirulence, 2022
One of the greatest achievements of the last century is the development of vaccines against viral diseases. Vaccines are essential for battling infectious diseases and many different formulations are available, including live attenuated vaccines. However,
Huai Xu   +5 more
doaj   +1 more source

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