Results 71 to 80 of about 2,422,081 (245)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Live bearing promotes the evolution of sociality in reptiles

Nature Communications, 2017
Live birth may be a precursor for parent-offspring associations and subsequent sociality, but the ubiquity of live birth in mammals and parental care in birds precludes testing the relationship in those clades.
Ben Halliwell, Tobias Uller, Barbara R. Holland, Geoffrey M. While   +3 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

The probability of preterm or early term second live births in the southern U.S. State of Georgia, 2011–2020

BMC Pregnancy and Childbirth
Background The extent to which past preterm or early term births are risk factors for recurrent shortened gestational age at delivery in the US is unclear.
Puneet Kaur Chehal, Maria Dieci, Zixuan Li, E. Kathleen Adams, Michael R. Kramer, Anne L. Dunlop   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

An assessment of the data quality for live births and infant deaths for the 1998-birth cohort, city of São Paulo, using information from SINASC and SIM [PDF]

In this article we use data from the 1998 birth-cohort from the City of São Paulo for live births and data on deaths from the same birth cohort that took place before the first year of life.
Carla Jorge Machado
core  

Risk of placenta previa in second birth after first birth cesarean section: a population-based study and meta-analysis. [PDF]

, 2011
OBJECTIVE: To compare the risk of placenta previa at second birth among women who had a cesarean section (CS) at first birth with women who delivered vaginally.
Onwere, Chidimma, Chidimma Onwere, David A Cromwell, Gordon CS Smith, Cromwell, David A., Gurol-Urganci, Ipek, Mahmood, Tahir A, Smith, Gordon C S, Smith, Gordon CS, van der Meulen, Jan H, Edozien, Leroy C., Tahir A Mahmood, Leroy C Edozien, Jan H van der Meulen, Templeton, Allan, Cromwell, David A, Mahmood, Tahir A., Edozien, Leroy C, van der Meulen, Jan H., Allan Templeton, Ipek Gurol-Urganci, Onwere Chidimma, Edozien Leroy C, Cromwell David A, Mahmood Tahir A, Smith Gordon CS, Gurol-Urganci Ipek, van der Meulen Jan H, Templeton Allan   +28 more
core   +4 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Risk ratios for prior live birth now dead for mothers with at least one prior live birth.

, 2023
Risk ratios for prior live birth now dead for mothers with at least one prior live birth.
Sushama Murthy (16907581), Jan-Marino Ramirez (400382), Darren Tanner (816669), Edwin A. Mitchell (7794206), Juan M. Lavista Ferres (13919431)   +4 more
core   +1 more source