Results 101 to 110 of about 8,368,948 (289)

The association between season and meteorological factors on clinical outcomes after fresh embryo transfer: a cohort study from Central Plains, China

Frontiers in Endocrinology
ObjectiveTo investigate whether seasonal variations and meteorological factors influence pregnancy outcomes in women undergoing in vitro fertilization/Intracytoplasmic sperm injection and embryo transfer(IVF/ICSI-ET) treatment.Materials and methodsWe ...
Hao Li, Xin Li, JinYu Li, YuMeng Ma, Gang Li   +4 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

The effect of transferring a low-quality embryo along with a high-quality embryo on the pregnancy outcome

Middle East Fertility Society Journal
Background Previous evidence suggests that low-quality embryos may send negative signals to the endometrium and affect the receptivity of the endometrium.
Xianju Huang, Xinle Lu, Xue Jiang, Ludan Chao, Xiao Wang   +4 more
doaj   +1 more source

DuoStim Shows Comparable Efficacy but Better Efficiency than Two Conventional Stimulations in Poor/Suboptimal Responders Undergoing Vitrified Oocyte Accumulation for PGT-A

Life
This study compared the DuoStim protocol with two conventional follicular phase stimulations for vitrified oocyte accumulation in poor-prognosis patients undergoing PGT-A.
Stefano Canosa, Alberto Revelli, Danilo Cimadomo, Alberto Vaiarelli, Gianluca Gennarelli, Daniela Guidetti, Andrea Roberto Carosso, Laura Rienzi, Filippo Maria Ubaldi, Francesca Bongioanni   +9 more
doaj   +1 more source

An assessment of the data quality for live births and infant deaths for the 1998-birth cohort, city of São Paulo, using information from SINASC and SIM [PDF]

In this article we use data from the 1998 birth-cohort from the City of São Paulo for live births and data on deaths from the same birth cohort that took place before the first year of life.
Carla Jorge Machado
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Birth Defects in Northern Iran (2008-2013)

Iranian Journal of Public Health, 2018
Background: Congenital anomalies are important medical and public health conditions. The pattern and prevalence of birth defects may vary over time or with geographical location.
Arezoo MIRFAZELI, Nafiseh KAVIANY, Kanizreza HOSSEINPOOR, Mohammad ARYAIE, Mohammad Jafar GOLALIPOUR   +4 more
doaj  

Data_Sheet_1_Major Factors Affecting the Live Birth Rate After Frozen Embryo Transfer Among Young Women.PDF

, 2020
In recent years, the freeze-all strategy has been widely adopted and applied. However, with the exception of age, the factors that affect the outcomes of frozen embryo transfer are still unclear.
Yuhua Shi (379491), Qiumin Wang (8613312), Hong Liu (50694), Qi Jiang (33521), Ze Wang (132986), Ye Pan (422909), Zi-Jiang Chen (130783), Guimin Hao (4864579)   +7 more
core   +1 more source