Results 81 to 90 of about 1,055,001 (304)

Socioeconomic inequalities in pregnancy outcome associated with Down syndrome: a population-based study. [PDF]

, 2015
OBJECTIVE: To investigate socioeconomic inequalities in outcome of pregnancy associated with Down syndrome (DS) compared with other congenital anomalies screened for during pregnancy.
Ahmed, Alderdice, Aslan, Brown, Brun, Chenni, Chiang, De Souza, Elizabeth S Draper, Evans, Feijen-de Jong, Garcia, Heyman, Judith L S Budd, Khoshnood, Kirwan, Kramer, Kupek, Kurinczuk, Laura E Berry, Liamputtong, Lucy K Smith, Lupton, Markens, Morris, Noble, Oakley, Oehlert, Pilnick, Robyn R Lotto, Rowe, Rowe, Smith, Tararbit, Williams   +34 more
core   +1 more source

Cumulative pregnancy and live birth rates after gamete intra-Fallopian transfer [PDF]

Human Reproduction, 1997
To evaluate the efficacy of gamete intra-Fallopian transfer (GIFT) the Kaplan-Meier life table method was used to analyse a patient cohort treated with GIFT between 1991 and 1994. In a tertiary referral centre for reproductive medicine, 1628 women with a median age of 33 years and various causes of infertility were included to calculate cumulative ...
L, Rombauts, M, Dear, S, Breheny, D L, Healy   +3 more
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Enterocolite necrosante: experiência de catorze anos [PDF]

, 2012
Backgound: Necrotizing enterocolitis ((NEC) is one of most frequent gastrointestinal emergencies in the neonatal period. Aims: To evaluate the incidência, epidemiology, risk factors and clinical outcomes of newborns with necrotizing enterocolitis ...
Faria, D, Ferreira, S, Paul, A, Resende, C   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ultrastructure of cytoplasmic fragments in human cleavage stage embryos [PDF]

, 2016
Purpose: The goal of this study was to evaluate the ultrastructure of cytoplasmic fragments along with the effect of cytoplasmic fragment and perivitelline space coarse granulation removal (cosmetic microsurgery) from embryos before embryo transfer on ...
Esfandiari, N., Halvaei, I., Khalili, M. A., MIGLIETTA, SELENIA, NOTTOLA, Stefania Annarita, Safari, S., Talebi, A. R.   +6 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Evaluation of neural tube defects from 2014 to 2019 in Turkey

BMC Pregnancy and Childbirth, 2022
Objective The aim of this study is to determine the frequency of neural tube defects (NTDs) and to examine the epidemiological characteristics of NTD related deaths in Turkey.
Nilgün Çaylan, Sıddıka Songül Yalçin, Başak Tezel, Şirin Aydin, Oben Üner, Fatih Kara   +5 more
doaj   +1 more source

Annual Summary of Vital Statistics-2001 [PDF]

, 2002
The number of births, the crude birth rate (14.5 in 2001), and the fertility rate (67.2 in 2001) all declined slightly (by 1% or less) from 2000 to 2001.
Guyer, Bernard, MacDorman, Marian F, Minino, Arialdi M, Strobino, Donna M   +3 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source