Results 41 to 50 of about 335,762 (303)

Current status of vaccine research, development, and challenges of vaccines for Mycoplasma gallisepticum

Poultry Science, 2020
Mycoplasma gallisepticum (MG) is an important avian pathogen that causes significant economic losses in the poultry industry. Surprisingly, the limited protection and adverse reactions caused by the vaccines, including live vaccines, bacterin-based ...
Muhammad Ishfaq, Wanying Hu, Mohammad Zeb Khan, Ijaz Ahmad, Wenxin Guo, Jichang Li   +5 more
doaj   +1 more source

Criteria for judging the immune markers of COVID‐19 disease vaccines

MedComm, 2022
As severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) sweeping the world, effective and affordable vaccines are in urgent need. A reliable system for the assessment of SARS‐CoV‐2 vaccines would boost the development of vaccines and reduce the ...
Nan Lin, Haoxuan Fu, Dan Pu, Yuxin Quan, Yueyi Li, Xiaomeng Yin, Yuhao Wei, Hang Wang, Xuelei Ma, Xiawei Wei   +9 more
doaj   +1 more source

Fructose potentiates the protective efficiency of live Edwardsiella tarda cell vaccine

Frontiers in Immunology, 2023
Vaccination is an effective measure to prevent infection by pathogens. Live vaccines have higher protective efficacy than inactivated vaccines. However, how live vaccines interact with the host from a metabolic perspective is unknown.
Chao Wang, Chao Wang, Xuan-xian Peng, Xuan-xian Peng, Hui Li, Hui Li   +5 more
doaj   +1 more source

Live viral vaccines in transplanted patients

Swiss Medical Weekly, 2014
Live attenuated viral vaccines (LAVV) have been used safely and with great success for decades to protect healthy patients against sometimes life-threatening diseases.
Arnaud G. L’Huillier, Klara Posfay Barbe   +1 more
doaj   +1 more source

Towards Improved Use of Vaccination in the Control of Infectious Bronchitis and Newcastle Disease in Poultry: Understanding the Immunological Mechanisms

Vaccines, 2021
Infectious bronchitis (IB) and Newcastle disease (ND) are two important diseases of poultry and have remained a threat to the development of the poultry industry in many parts of the world.
Anthony C. Ike, Chukwuebuka M. Ononugbo, Okechukwu J. Obi, Chisom J. Onu, Chinasa V. Olovo, Sophia O. Muo, Okoro S. Chukwu, Eleazar E. Reward, Odinakachukwu P. Omeke   +8 more
doaj   +1 more source

Recombinant anticoccidial vaccines - a cup half full? [PDF]

, 2017
Eimeria species parasites can cause the disease coccidiosis, most notably in chickens. The occurrence of coccidiosis is currently controlled through a combination of good husbandry, chemoprophylaxis and/or live parasite vaccination; however, scalable ...
Ahmad, Arnott, Awad, Bafundo, Blake, Blake, Blake, Brothers, Brown, Chapman, Chapman, Chapman, Chapman, Chapman, Chapman, Chapman, Chapman, Chen, Clark, Clark, Cornelissen, Cosentino, Crane, Dalloul, Damer P. Blake, Ding, Ding, Djemai, Du, Eckford, Fiona M. Tomley, Fischbach, Fluit, Gedik, Gowen, Hedhli, Hoan, Huang, Iván Pastor-Fernández, Jahn, Jang, Jang, Jenkins, Jenkins, Jenkins, Jiang, Joyner, Karlsson, Keestra, Klotz, Koblansky, Konjufca, Kundu, Kvicerova, Labbe, Lai, Lassen, Lee, Li, Li, Lillehoj, Liu, Long, Marugan-Hernandez, Matthew J. Nolan, McDonald, McDonald, Min, Naciri, Nolan, Peek, Peek, Plattner, Pogonka, Reid, Ruff, Rugarabamu, Salazar Gonzalez, Sathish, Schaap, Shah, Sharman, Shen, Shirley, Shirley, Smith, Song, Song, Song, Song, Song, Song, Song, Subramanian, Sun, Takala, Tang, Tomley, Tomley, Tomley, Vermeulen, Vrba, Wallach, Wang, Wang, Williams, Williams, Williams, Williams, Williams, Witcombe, Wu, Xu, Xu, Yin, Yin, Yun, Zhang, Zhang, Zimmermann   +119 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Single-Dose Immunogenic DNA Vaccines Coding for Live-Attenuated Alpha- and Flaviviruses

Viruses
Single-dose, immunogenic DNA (iDNA) vaccines coding for whole live-attenuated viruses are reviewed. This platform, sometimes called immunization DNA, has been used for vaccine development for flavi- and alphaviruses.
Peter Pushko, Igor S. Lukashevich, Dylan M. Johnson, Irina Tretyakova   +3 more
doaj   +1 more source

A New Live Auxotrophic Vaccine Induces Cross-Protection against Klebsiella pneumoniae Infections in Mice

Vaccines, 2022
The development of a whole-cell vaccine from bacteria auxotrophic for D-amino acids present in the bacterial cell wall is considered a promising strategy for providing protection against bacterial infections.
Miriam Moscoso, Juan A. Vallejo, Maria P. Cabral, Patricia García, Víctor Fuentes-Valverde, Eva Gato, Jorge Arca-Suárez, Pablo Aja-Macaya, Germán Bou   +8 more
doaj   +1 more source

Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium [PDF]

, 2019
Funding text The authors are grateful for the vital contributions of the participating study volunteers, clinicians, nurses, and laboratory technicians at the Surrey study site.
Bodinham, C., Bottazzi, B., DelGiudice, G., Denoel, P., Greenwood, A., Jonsdottir, I., Kaufmann, S., Kester, K., Leroux-Roels, G., Lewis, D., Linley, C., Maertzdorf, J., Mantovani, A., Mollenkopf, H., Pizzoferro, K., van den Berg, R., Weiner, J.   +16 more
core   +1 more source