Results 71 to 80 of about 1,888,131 (358)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Pandemic impact, mitigation strategies and peer support: a qualitative analysis of youth, parent, clinician and administrator perspectives

Journal of Eating Disorders
Objectives This study describes views on the impact of the COVID-19 pandemic on eating disorder symptoms in youth, as well as the impact on care, and the possibility of peer support as a mitigating strategy from the perspectives of youth and parents with
Jennifer Couturier, Maria Nicula, Cheryl Webb, Gina Dimitropoulos, Nicole Obeid, Melissa Kimber, Techiya Loewen, Anne Marie Coolen, Erica Crews, Shaleen Jones, Cendrine Tremblay, Wendy Preskow, Gail McVey, Lori Wozney   +13 more
doaj   +1 more source

Decision letter for "Lived experience of neuropsychiatric symptoms among females with mild cognitive impairment: A phenomenological study"

, 2021

openalex   +1 more source

Food Security for People with Lived-Refugee Experiences is Interrelated with Culture and Mental Health: Perspectives from Workers Supporting the Settlement Journey in Australia [PDF]

, 2023
Tina Gingell, Nehal Eltahir, Evelyn Pe, Kate Murray, Ignacio Correa‐Velez, Danielle Gallegos   +5 more
openalex   +1 more source

Writing as life performed [PDF]

, 2014
In this chapter I explore the interrelatedness of practice, rehearsal, and performance and their applicability in the domain of “life.” These relationships are complicated when, in reference to Adorno’s Minima Moralia, the content of critical-essayistic ...
Parker Dixon, Martin J.C.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Irreducible Aspects of Embodiment: Situating Scientist and Subject [PDF]

, 2018
Feminist philosophers of science have long discussed the importance of taking situatedness into account in scientific practices to avoid erasing important aspects of lived experience. Through the example of Gillian Einstein’s [2012] situated neuroscience,
Brancazio, Nick
core  

Playing with the future: social irrealism and the politics of aesthetics [PDF]

, 2013
In this paper we wish to explore the political possibilities of video games. Numerous scholars now take seriously the place of popular culture in the remaking of our geographies, but video games still lag behind.
Bramwell T., Brooker C., Brown J., Cain J.P., Darrall S., Dittmer J., Flanagan M., Foucault M., Haraway D.J., Hope J., Ian G.R. Shaw, IGN, Joanne P. Sharp, Kneale J., Lomberg J., Massumi B., Musgrove M., Thomas N.   +17 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Parents with learning disabilities - the lived experience - a study for equal say, Glasgow [PDF]

, 2008
In order to more clearly identify the key issues with regard to parents with learning disabilities, Equal Say commissioned the Glasgow School of Social Work to undertake a small pilot study which aimed to: identify the likely demand for advocacy services
MacIntyre, Gillian, Stewart, Ailsa, University of Strathclyde   +2 more
core   +1 more source