Results 71 to 80 of about 4,828,104 (248)

“Just a number” – larger-bodied women’s experiences of weight-centric and weight-inclusive maternity care: a national online photovoice study

BMC Pregnancy and Childbirth
Background Weight stigma is a pervasive issue in healthcare, including maternity care, characterised by bias, discrimination, and exclusion. Experiencing weight stigma can negatively impact health outcomes, self-esteem, and engagement with care.
Bec Jenkinson, Lauren Kearney, Ahlia Griffiths, Brianne Mackinnon, Sara B. Gill, Briony Hill, Renee Tome, Tina Siale, Kayla Barrow, Laura Hewett, Tanya Cawthorne, Jennifer Hocking, Jacqueline A Boyle, Leonie Callaway   +13 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Who gets to decide? Matters arising from Robinson et al. (2024), “Can people with longstanding bulimia nervosa suffer from severe and enduring eating disorder? A qualitative study”

Journal of Eating Disorders
Written by a researcher with lived experience of long-standing bulimia nervosa, this Matters Arising piece commends Robinson et al. (2024)’s study for its focus on exploring the subjective experiences of patients who are often overlooked in clinical and ...
James Downs
doaj   +1 more source

The lived experience of parenting a child with a life-limiting condition: A focus on the mental health realm [PDF]

, 2009
Objective: As medical technology has improved, there has been a marked increase in the numbers of children with life-limiting conditions being managed in the community. Few studies have evaluated the life worlds of the parents of these children. However,
King, Nigel, Rodriguez, Alison
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The lived experience of mental health service users in a UK community rehabilitation scheme

, 2008
The scarcity of research on mental health service with lived experience using community rehabilitation services has become an area of research study relating to one UK community rehabilitation ...
Kowlessar, O., Corbett, K.
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Collective responsibility and ecological thinking in eating disorders: moving beyond individualistic models of illness and recovery

Journal of Eating Disorders
Eating disorder treatment and recovery are often framed as matters of individual responsibility, with change positioned as dependent on the person’s motivation, insight, and willingness to recover.
James Downs
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Development of the Japanese Version of the Views on Inpatient Care (VOICE-J): Service Users’ Perspectives on Psychiatric Inpatient Care

Journal of Patient Experience
The quality of psychiatric inpatient care is a pressing concern in Japan, where hospitalization is prolonged and coercive practices remain common. Incorporating patients’ perspectives is essential for evaluation and service improvement.
Yuki Miyamoto RN, PHN, PhD, Risa Kotake RN, MSc, Emiko Otsu-Mitsui MSN, RN, PHN, CNS, Manami Tsunemoto, Tomoko Shinmura, Utako Sawada RN, PhD, Kaori Tsuzuki, Neteru Masukawa, Jo Evans MA, MSc, Daisuke Nishi MD, PhD   +9 more
doaj   +1 more source