Results 171 to 180 of about 2,738,593 (315)

Newly Established Anoikis-Associated Genes Predict the Prognosis of Hepatocellular Carcinoma

open access: yesJournal of Hepatocellular Carcinoma
Yuyao Li,1,* Er Li,2,* Wenlan Zheng,1 Jia Shi,1 Shihan Yu,1 Xuemei Zhang,1 Liming Zheng,1 Wurong Du,1 Hao Liu,1 Hai Feng,2 Jianfeng Guo,3 Zhuo Yu1 1Department of Liver Disease, Shuguang Hospital Affiliated to Shanghai University of ...
Li Y   +11 more
doaj  

GDF-15 Levels in Cirrhosis Are Linked to Hepatic Fibrogenesis, Bacterial Translocation, and Worse Clinical Outcomes. [PDF]

open access: yesLiver Int
Hofer BS   +22 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Trends of Advanced Chronic Liver Disease Among 17,711 Persons in Mongolia During Years 2015-2023. [PDF]

open access: yesJ Viral Hepat
Kamal H   +11 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Antiseizure Treatments and Liver Injury: Expect (and Prevent) the Unexpected. [PDF]

open access: yesEpilepsy Curr
Bunch M   +4 more
europepmc   +1 more source

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