Results 11 to 20 of about 2,047,983 (266)

Liver [PDF]

Modern Pathology, 2016
The median waiting time for patients with MELD ≥ 35 decreased from 18 days in 2012 to 9 days in 2014, after implementation of the Share 35 policy in June 2013. Similarly, mortality among candidates listed with MELD ≥ 35 decreased from 366 per 100 waitlist years in 2012 to 315 in 2014.
W R, Kim, J R, Lake, J M, Smith, M A, Skeans, D P, Schladt, E B, Edwards, A M, Harper, J L, Wainright, J J, Snyder, A K, Israni, B L, Kasiske   +10 more
  +9 more sources

Liver metastases

Nature Reviews Disease Primers, 2021
Liver metastases are commonly detected in a range of malignancies including colorectal cancer (CRC), pancreatic cancer, melanoma, lung cancer and breast cancer, although CRC is the most common primary cancer that metastasizes to the liver. Interactions between tumour cells and the tumour microenvironment play an important part in the engraftment ...
Tsilimigras, Diamantis I, Brodt, Pnina, Clavien, Pierre-Alain, Muschel, Ruth J, D’Angelica, Michael I, Endo, Itaru, Parks, Rowan W, Doyle, Majella, de Santibañes, Eduardo, Pawlik, Timothy M   +9 more
openaire   +4 more sources

ِAnalysis of donor motivations in living donor liver transplantation

Frontiers in Surgery, 2014
Objectives: The introduction of the living donor liver transplantation (LDLT) in Egypt as in elsewhere, has raised important psychological conflicts and ethical questions.
Hesham eAbdeldayem, Samy eKashkoush, Bassem Soliman Hegab, Amr eAziz, Hany eShoreem, Shereef eSaleh   +5 more
doaj   +1 more source

Liver Regeneration after Liver Transplantation [PDF]

European Surgical Research, 2012
<b><i>Background/Purpose:</i></b> The liver has a remarkable capacity to regenerate after injury or resection. The aim of this review is to outline the mechanisms and factors affecting liver regeneration after liver transplantation.
A, Taki-Eldin, L, Zhou, H-Y, Xie, S-S, Zheng   +3 more
openaire   +2 more sources

Liver regeneration [PDF]

Journal of Cellular Physiology, 2007
AbstractLiver regeneration after partial hepatectomy is a very complex and well‐orchestrated phenomenon. It is carried out by the participation of all mature liver cell types. The process is associated with signaling cascades involving growth factors, cytokines, matrix remodeling, and several feedbacks of stimulation and inhibition of growth related ...
openaire   +2 more sources

The impact of tumor burden at the initial hepatectomy on the recurrence-to-death survival after repeat surgical resection/radiofrequency ablation: a retrospective study

BMC Surgery, 2022
Background Previous studies have reported the surgical resection (SR) and radiofrequency ablation (RFA) could achieve comparable recurrence-to-death survival (RTDS).
Youwei Wu, Wei Peng, Junyi Shen, Xiaoyun Zhang, Chuan Li, Tianfu Wen   +5 more
doaj   +1 more source

The Efficacy and Safety of Hepatic Arterial Infusion Chemotherapy Based on FOLFIRI for Advanced Intrahepatic Cholangiocarcinoma as Second-Line and Successive Treatment: A Real-World Study

Canadian Journal of Gastroenterology and Hepatology, 2022
Objective. Intrahepatic cholangiocarcinoma (iCCA) is a primary liver malignancy with a poor prognosis and limited treatment. Cisplatin with gemcitabine is used as the standard first-line chemotherapy regimen; however, there is still no robust evidence ...
Peixin Huang, Xiaoyong Huang, Yingting Zhou, Guohuan Yang, Qiman Sun, Guoming Shi, Yi Chen   +6 more
doaj   +1 more source

SQSTM1/p62 in intrahepatic cholangiocarcinoma promotes tumor progression via epithelial–mesenchymal transition and mitochondrial function maintenance

Cancer Medicine, 2023
Background SQSTM1/p62 is a selective autophagy receptor that regulates multiple signaling pathways participating in the initiation and progression of tumors.
Jiafeng Chen, Zheng Gao, Xiaogang Li, Yinghong Shi, Zheng Tang, Weiren Liu, Xin Zhang, Ao Huang, Xuanming Luo, Qiang Gao, Guangyu Ding, Kang Song, Jian Zhou, Jia Fan, Xiutao Fu, Zhenbin Ding   +15 more
doaj   +1 more source

Liver Transplantation [PDF]

Seminars in Liver Disease, 1999
Since the first human liver transplant done in 1963, the procedure has become a routine procedure with an excellent outcome in terms both of quality and of length of survival. The development and introduction into clinical practice of a variety of immunosuppressive agents has given the clinician a bewildering array of therapeutic options but with a ...
openaire   +4 more sources

Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma

Cancer Cell International, 2019
Background Oxaliplatin-based chemotherapy is widely used to treat hepatocellular carcinoma (HCC). Recent studies suggested that therapeutic resistance of tumors was affected by tumor microenvironment (TME).
Xiu-Tao Fu, Kang Song, Jian Zhou, Ying-Hong Shi, Wei-Ren Liu, Guo-Ming Shi, Qiang Gao, Xiao-Ying Wang, Zhen-Bin Ding, Jia Fan   +9 more
doaj   +1 more source