Results 211 to 220 of about 4,693,650 (362)

Management of acute liver failure-an updated literature review. [PDF]

World J Crit Care Med
Nagesh VK, Martinez E, Badam S, Harrison JL, Basta M, Varughese VJ, Anwar GR, Deshpande V, Francis D, Islek D, Pulipaka SP, Bhuju R, Moliya P, Niazi B, Elias S.   +14 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Metabolic dysfunction-associated steatohepatitis is the leading indication for adult liver transplantation in Saudi Arabia. [PDF]

PLoS One
Alqahtani SA, AlMuhaidib S, Raptis DA, Al-Hamoudi WK, Reddy KR, Broering DC, Alghamdi SA, OTCE Collaborative.   +7 more
europepmc   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

NAD + in fatty liver disease: mechanistic insights and associated targets. [PDF]

Cell Biol Toxicol
Guo Y, Wang Y, Wu S, Wang Y, Liu X.
europepmc   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Newly Established Anoikis-Associated Genes Predict the Prognosis of Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma
Yuyao Li,1,* Er Li,2,* Wenlan Zheng,1 Jia Shi,1 Shihan Yu,1 Xuemei Zhang,1 Liming Zheng,1 Wurong Du,1 Hao Liu,1 Hai Feng,2 Jianfeng Guo,3 Zhuo Yu1 1Department of Liver Disease, Shuguang Hospital Affiliated to Shanghai University of ...
Li Y, Li E, Zheng W, Shi J, Yu S, Zhang X, Zheng L, Du W, Liu H, Feng H, Guo J, Yu Z   +11 more
doaj  

A surprising new hiding place for a dangerous pathogen. [PDF]

Elife
Gandotra S, Singh Y.
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Empagliflozin-Induced Liver Injury. [PDF]

Eur J Case Rep Intern Med
Gonçalves HD, Parreira I, Vasconcelos-Teixeira S, Melício A, Dias M, Madeira Lopes J, Duarte L.   +6 more
europepmc   +1 more source