Results 51 to 60 of about 6,238,038 (408)

Liver metastases

Nature Reviews Disease Primers, 2021
Liver metastases are commonly detected in a range of malignancies including colorectal cancer (CRC), pancreatic cancer, melanoma, lung cancer and breast cancer, although CRC is the most common primary cancer that metastasizes to the liver. Interactions between tumour cells and the tumour microenvironment play an important part in the engraftment ...
Tsilimigras, Diamantis I, Brodt, Pnina, Clavien, Pierre-Alain, Muschel, Ruth J, D’Angelica, Michael I, Endo, Itaru, Parks, Rowan W, Doyle, Majella, de Santibañes, Eduardo, Pawlik, Timothy M   +9 more
openaire   +4 more sources

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

Population Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source

Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]

, 2016
OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou, Alvarez, Block, Boonstra, Deneau, Dotson, Faubion, Feldstein, Goyal, Gregorio, Halliday, Hirschfield, Hov, Jose, Jose, Levine, Levine, Liberal, Loftus, Loftus, Lundqvist, Maggiore, Malaty, Mieli-Vergani, Navaneethan, Noble-Jamieson, Olsson, Ordonez, Penna, Rönnblom, Sokol, Zholudev   +31 more
core   +1 more source

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco, Francis, Heather, Kennedy, Lindsey, Kundu, Debjyoti, Meadows, Vik   +4 more
core   +1 more source

Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single-center, single-arm, phase 2 study

Signal Transduction and Targeted Therapy, 2023
Advanced intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis. Here, we report the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin (GEMOX) as first-line therapy for advanced ICC.
Guo-Ming Shi, Xiao-Yong Huang, Dong Wu, Hui-Chuan Sun, Fei Liang, Yuan Ji, Yi Chen, Guo-Huan Yang, Jia-Cheng Lu, Xian-Long Meng, Xin-Ying Wang, Lei Sun, Ning-Ling Ge, Xiao-Wu Huang, Shuang-Jian Qiu, Xin-Rong Yang, Qiang Gao, Yi-Feng He, Yang Xu, Jian Sun, Zheng-Gang Ren, Jia Fan, Jian Zhou   +22 more
doaj   +1 more source

Between Droughts and Floods: The Seasonal Response of Freshwater Snails in Artificial Reservoirs in the Brazilian Semiarid Region

Population Ecology, EarlyView.
We investigate the seasonal dynamics of two freshwater snails, Biomphalaria straminea and Melanoides tuberculata, in artificial reservoirs of the Brazilian semiarid region. Despite regulated hydrology, B. straminea exhibited strong seasonal fluctuations associated with dry periods, while M. tuberculata maintained stable populations throughout the year,
Lucas Henrique Sousa da Silva, João Hemerson de Sousa, Adriana Josefa da Rocha, Manuella Feitosa Leal, Lucas Ariel de Sousa Aguiar, Tamaris Gimenez Pinheiro, Edson Lourenço da Silva   +6 more
wiley   +1 more source

Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human

, 2019
The Hedgehog (Hh) and Wnt/β-Catenin (Wnt) cascades are morphogen pathways whose pronounced influence on adult liver metabolism has been identified in recent years.
Aleithe, S., Brosch, M., Brusch, L., Damm, G., Gajowski, R., Gebhardt, R., Hampe, J., Hoehme, S., Hoffmann, U., Kolbe, E., Kücken, M., Matz-Soja, M., Meierhofer, D., Ott, F., Rennert, C., Schafmayer, C., Seehofer, D., Seifert, M., Spormann, L., Stöpel, C., von Schoenfels, W.   +20 more
core   +1 more source

CD4+CD25+CD127low regulatory T cells play predominant anti-tumor suppressive role in hepatitis B virus associated hepatocellular carcinoma

Frontiers in Immunology, 2015
Background:Hepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide and hepatitis B is one of the commonest causes. T regulatory cells (Tregs) are strong immunomodulators and are likely to play a major role in HCC development.
Shreya eSharma, Ritu eKhosla, Paul eDavid, Archana eRastogi, Ashish eVyas, Dileep eSingh, Ankit eBhardwaj, Amrish eSahney, Rakhi eMaiwall, Shiv Kumar Sarin, Nirupma eTrehanpati   +10 more
doaj   +1 more source

Serial circulating tumor DNA to predict early recurrence in patients with hepatocellular carcinoma: a prospective study

Molecular Oncology, 2022
We studied the value of circulating tumor DNA (ctDNA) in predicting early postoperative tumor recurrence and monitoring tumor burden in patients with hepatocellular carcinoma (HCC).
Gui‐Qi Zhu, Wei‐Ren Liu, Zheng Tang, Wei‐Feng Qu, Yuan Fang, Xi‐Fei Jiang, Shu‐Shu Song, Han Wang, Chen‐Yang Tao, Pei‐Yun Zhou, Run Huang, Jun Gao, Hai‐Xiang Sun, Zhen‐Bin Ding, Yuan‐Fei Peng, Zhi Dai, Jian Zhou, Jia Fan, Ying‐Hong Shi   +18 more
doaj   +1 more source

Resolving the fibrotic niche of human liver cirrhosis at single cell level

Nature, 2019
Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available.
P. Ramachandran, R. Dobie, J. Wilson-Kanamori, Elena Dorà, Beth E. P. Henderson, N. Luu, N. Luu, J. R. Portman, Kylie P. Matchett, M. Brice, John A. Marwick, R. S. Taylor, M. Efremova, R. Vento-Tormo, N. Carragher, T. Kendall, J. Fallowfield, E. Harrison, D. Mole, D. Mole, S. Wigmore, S. Wigmore, Phil N. Newsome, Phil N. Newsome, C. Weston, C. Weston, J. Iredale, Frank Tacke, J. Pollard, J. Pollard, C. Ponting, J. Marioni, J. Marioni, S. Teichmann, Sarah A. Teichmann, N. Henderson   +35 more
semanticscholar   +1 more source