Results 71 to 80 of about 2,769,816 (316)

Liver regeneration

Journal of Hepatology, 2006
During liver regeneration after partial hepatectomy, normally quiescent hepatocytes undergo one or two rounds of replication to restore the liver mass by a process of compensatory hyperplasia. A large number of genes are involved in liver regeneration, but the essential circuitry required for ...
Fausto, Nelson, Campbell, Jean S., Riehle, Kimberly J.   +2 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Total-liver-volume perfusion CT using 3-D image fusion to improve detection and characterization of liver metastases

, 2008
The purpose of this study was to evaluate the feasibility of a totalliver- volume perfusion CT (CTP) technique for the detection and characterization of livermetastases.
Cornelis van Kuijk, van Waesberghe, Jan, Meijer, Sybren, Weide, Lineke van der, Sybren Meijer, van Kuijk, C., van den Tol, Petrousjka, Lineke van der Weide, van den Tol, M.P., van der Weide, L., Meijer, S., van der Weide, Lineke, Meijerink, Martijn, Martijn R. Meijerink, Jan Hein T. M. van Waesberghe, Meijerink, M.R., van Waesberghe, J.H.T.M., Kuijk, Cornelis van, Petrousjka van den Tol, Waesberghe, Jan van, Tol, Petrousjka van den   +20 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Living donor liver transplantation for acute liver failure in pediatric patients caused by the ingestion of fireworks containing yellow phosphorus

, 2011
Yellow phosphorus is a protoplasmic toxicant that targets the liver. The ingestion of fireworks containing yellow phosphorus, either by children who accidentally consume them or by adults who are attempting suicide, often results in death due to acute ...
Işık, Burak, Selimoğlu, Mukadder Ayşe, Kayaalp, Cüneyt, Yılmaz, Sezai, Aydın, Cemalettin, Ara, Cengiz, Ateş, Mustafa, Yılmaz, Mehmet, Özgör, Dinçer, Dirican, Abuzer   +9 more
core  

The utility of liver function tests for mortality prediction within one year in primary care using the algorithm for liver function investigations (ALFI) [PDF]

, 2012
BACKGROUND: Although liver function tests (LFTs) are routinely measured in primary care, raised levels in patients with no obvious liver disease may trigger a range of subsequent expensive and unnecessary management plans.
Roderick Paul, Donnan, Peter T, John F. Dillon (110507), Stephen D Ryder, McLernon, DJ, Rosenberg, WM, McLernon, D.J., McLernon David J., Roderick, P., William M. Rosenberg (110512), Roderick, Paul, Donnan, PT, Dillon, John F.; id_orcid, McLernon, David J., David J McLernon, Rosenberg, William M, Paul Roderick, Donnan, Peter T.; id_orcid, Sullivan, F.M., Dillon, J.F., Ryder, Stephen D., Sullivan, Frank M, Ryder, S.D., McLernon, David J, Rosenberg, William M., Dillon, John F., John F Dillon, Peter T. Donnan (110517), Donnan, Peter T., Roderick, P, Paul Roderick (14856), Donnan, P.T., Sullivan, FM, Ryder Stephen D., Sullivan Frank M., David J. McLernon (110505), Donnan Peter T., Peter T Donnan, Dillon, John F, Rosenberg, W.M., Frank M Sullivan, Rosenberg William M., Ryder, SD, Dillon, JF, Frank M. Sullivan (110508), William M Rosenberg, Sullivan, Frank M., Ryder, Stephen D, Dillon John F., Stephen D. Ryder (110515)   +49 more
core   +1 more source

Liver regeneration [PDF]

Journal of Cellular Physiology, 2007
AbstractLiver regeneration after partial hepatectomy is a very complex and well‐orchestrated phenomenon. It is carried out by the participation of all mature liver cell types. The process is associated with signaling cascades involving growth factors, cytokines, matrix remodeling, and several feedbacks of stimulation and inhibition of growth related ...
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Liver stiffness, a non-invasive marker of liver disease: a core study group report [PDF]

, 2010
liver ...
Pinzani, M, Liver Stiffness Study Group 'Elastica' of the Italian Association for the Study of the Liver, Prati, D, Pinzani M, CRAXI, Antonio, Rigamonti C, Vizzuti, F, Brunetto, MR, Coco B, Coco, B, Bonino, F, Fraquelli M, Prati D, Oliveri, F, Oliveri F, Rigamonti, C, Vizzuti F, Fraquelli, M, Arena U, Arena, U, Brunetto MR, Bonino F.   +21 more
core   +1 more source

Liver Transplantation [PDF]

Seminars in Liver Disease, 1999
Since the first human liver transplant done in 1963, the procedure has become a routine procedure with an excellent outcome in terms both of quality and of length of survival. The development and introduction into clinical practice of a variety of immunosuppressive agents has given the clinician a bewildering array of therapeutic options but with a ...
openaire   +4 more sources