Results 81 to 90 of about 2,769,816 (316)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Combination of Transient Elastography and an Enhanced Liver Fibrosis Test to Assess the Degree of Liver Fibrosis in Patients with Chronic Hepatitis B [PDF]

, 2018
Background/Aims: Liver stiffness (LS) was assessed using transient elastography, and the enhanced liver fibrosis (ELF) test was performed to accurately assess fibrotic burden.
안상훈, 박준용, 김도영, 김승업, 한광협, 김범경   +5 more
core   +1 more source

Hypoxia- and Anoikis-Related lncRNA Signature Defines Molecular Subtypes and Predicts Prognosis and Immunotherapy Response in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma
Xiaohang Lu,1– 3,* Yunyong Wang,1,3,* Yuan Yu,4 Rongzhen Zhang,5 Fuli Long,5 Minpeng Li,4 Meng Pan,4 Kewei Du,6 Jinna Tan,1,3 Jiaqian He,1,3 Zongxian Li,7,8 Hongsheng Lin,1,6,* Mingfen Li1,6,* 1The First Affiliated ...
Lu X, Wang Y, Yu Y, Zhang R, Long F, Li M, Pan M, Du K, Tan J, He J, Li Z, Lin H, Li M   +12 more
doaj  

Expert survey on systemic therapy indications for hepatocellular carcinoma in Korea: bridging clinical practice and reimbursement criteria [PDF]

Journal of Liver Cancer
This survey aimed to collect expert opinions from multidisciplinary specialists involved in the management of hepatocellular carcinoma (HCC) in Korea regarding real-world criteria for systemic therapy indications.
Hyun Yang, Soon Sun Kim, Seong Hee Kang, Jieun Kwon, Do Young Kim, Eunju Kim, Hyun Phil Shin, Jeong Il Yu, Jeong-Ju Yoo, Eileen L. Yoon, Sangheun Lee, Young Eun Chon, Janghan Jung, Jaekyung Cheon, Woosun Choi, Seul Ki Han, Ji Eun Han, Moon Haeng Hur, Hyun Woong Lee, Hyung Joon Kim   +19 more
doaj   +1 more source

The Liver in Brucellosis

Clinical Gastroenterology and Hepatology, 2007
Brucellosis involves the liver in varying ways, ranging from benign subclinical increases in serum aminotransferase levels to ominous chronic suppurative disease. Data on histopathology of the liver in brucellosis are scarce and contradictory. We sought to determine the liver histologic patterns present in a series of brucellosis patients and review ...
Akritidis, Nikolaos, Tzivras, Michael, Delladetsima, Ioanna, Stefanaki, Styliani, Moutsopoulos, Haralampos M., Pappas, Georgios   +5 more
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Liver resection versus liver transplantation as treatment of early hepatocellular carcinoma: a case-control study

, 2009
Background and aim. The choice of the best surgical strategy for early hepatocellular carcinoma (HCC) on well-compensated cirrhosis is still controversial.
Iemmolo RM, Rompianesi G, Di Benedetto F, Gerunda GE, Masetti M, De Ruvo N, Cautero N, Guerrini GP, Ballarin R, Montalti R, Serra V   +10 more
core  

Proposal of a new diagnostic algorithm for hepatocellular carcinoma based on the Japanese guidelines but adapted to the Western world for patients under surveillance for chronic liver disease

, 2016
To date, despite many scientific evidences, the guidelines of the principal hepatological societies, such as the American Association for the Study of Liver Diseases, the European Association for the Study of the Liver, and the Asian Pacific Association ...
Bologna Liver Oncology Group (BLOG), Renzulli, Matteo, Golfieri, Rita   +2 more
core   +1 more source

Orthotopic liver transplantation in human-immunodeficiency-virus-positive patients in Germany [PDF]

, 2012
Objectives: This summary evaluates the outcomes of orthotopic liver transplantation (OLT) of HIV-positive patients in Germany. Methods: Retrospective chart analysis of HIV-positive patients, who had been liver-transplanted in Germany between July ...
T. Sauerbruch, J. Kittner, S. Manekeller, A. Paul, Anadol, Evrim, Beckebaum, Susanne, Rockstroh, Jürgen, T. Ganten, Paul, Andreas, Bickel, Markus, J. C. Kalff, Spengler, Ulrich, E. Anadol, M. Stoll, Zoufaly, Alexander, S. Beckebaum, Kittner, Jens Martin, M. Bickel, Hitzenbichler, Florian, Stoll, Matthias, Kalff, Jörg C., A. Zoufaly, Manekeller, Steffen, Ganten, Tom M., C. Berg, F. Hitzenbichler, J. K. Rockstroh, Radecke, Klaus, K. Radecke, Berg, C., U. Spengler, Sauerbruch, Tilman   +31 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source