Results 101 to 110 of about 4,044,841 (310)
Pediatric liver transplantation [PDF]
, 1987 Liver transplantation, which once was an experimental procedure of no practical interest, has become the preferred treatment for infants and children dying of almost all non-neoplastic end-stage liver diseases. Liver replacement is being provided by many
Esquivel, C +3 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Animal models of NASH: getting both pathology and metabolic context right [PDF]
, 2015 Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Social Support, Quality of Life, and Financial Toxicity Among Patients with Hepatocellular Carcinoma
Journal of Hepatocellular CarcinomaShuyue Liu,1– 3,* Yawen Xie,1– 3,* Tiantian Li,1– 3,* Yanxia Huang,1– 3 Danting Xu,1– 3 Linli Cai,1– 3 Yizhen Fu,1– 3 Jinbin Chen,1– 3 Yaojun Zhang,1– 3 Jia Huang,4 Zili Hu1– 3 1Department of Liver Surgery, Sun Yat-Sen University ...
Liu S +10 more
doaj
Current Opinion in Gastroenterology, 2005 Liver transplantation continues to change as we further define appropriate criteria for allocation and utilization of this scarce resource. The following review highlights new trends and ideas in this evolving field.Although the model for end-stage renal disease (MELD) scoring system appears to fairly accurately predict mortality while waiting for ...
openaire +2 more sources
Liver lesion segmentation informed by joint liver segmentation
, 2018 We propose a model for the joint segmentation of the liver and liver lesions in computed tomography (CT) volumes. We build the model from two fully convolutional networks, connected in tandem and trained together end-to-end.
Kadoury, Samuel +3 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Liver transplantation in patients with situs inversus [PDF]
, 1990 Two patients with situs inversus and biliary atresia were treated with hepatic transplantation, one with an auxiliary liver and the other with an orthotopic graft which was placed using a piggy-back technique.
Hall, R, Starzl, TE, Todo, S, Tzakis, A
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source