Results 51 to 60 of about 1,087,915 (317)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Development and validation of a new tumor-based gene signature predicting prognosis of HBV/HCV-included resected hepatocellular carcinoma patients

Journal of Translational Medicine, 2019
Background Due to the phenotypic and molecular diversity of hepatocellular carcinomas (HCC), it is still a challenge to determine patients’ prognosis. We aim to identify new prognostic markers for resected HCC patients.
Gui-Qi Zhu, Yi Yang, Er-Bao Chen, Biao Wang, Kun Xiao, Shi-Ming Shi, Zheng-Jun Zhou, Shao-Lai Zhou, Zheng Wang, Ying-Hong Shi, Jia Fan, Jian Zhou, Tian-Shu Liu, Zhi Dai   +13 more
doaj   +1 more source

Circulating tumor cell detection and single‐cell analysis using an integrated workflow based on ChimeraX®‐i120 Platform: A prospective study

Molecular Oncology, 2021
Circulating tumor cell (CTC) analysis holds great potential to be a noninvasive solution for clinical cancer management. A complete workflow that combined CTC detection and single‐cell molecular analysis is required.
Peng‐Xiang Wang, Yun‐Fan Sun, Wei‐Xiang Jin, Jian‐Wen Cheng, Hai‐Xiang Peng, Yang Xu, Kai‐Qian Zhou, Li‐Meng Chen, Kai Huang, Sui‐Yi Wu, Bo Hu, Ze‐Fan Zhang, Wei Guo, Ya Cao, Jian Zhou, Jia Fan, Xin‐Rong Yang   +16 more
doaj   +1 more source

Cancer of the Liver [PDF]

The American Journal of the Medical Sciences
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openaire   +2 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Serum microRNA-122 predicts survival in patients with liver cirrhosis

, 2012
Background: Liver cirrhosis is associated with high morbidity and mortality. MicroRNAs (miRs) circulating in the blood are an emerging new class of biomarkers.
Stefan Zeuzem, Albrecht Piiper (22854), Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Verena Köberle (130993), Bernd Kronenberger (131004), Bernd Kronenberger, Verena Köberle, Waidmann, Oliver, Albrecht Piiper, Oliver Waidmann (130988), Piiper, Albrecht, Friederike Brunner (130998), Köberle, Verena, Brunner, Friederike, Zeuzem, Stefan, Stefan Zeuzem (22856)   +17 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Tumor associated macrophages-derived exosomes facilitate hepatocellular carcinoma malignance by transferring lncMMPA to tumor cells and activating glycolysis pathway

Journal of Experimental & Clinical Cancer Research, 2022
Background Tumor-associated macrophages (TAMs), which form a large part of the tumor microenvironment, are normally regulated by metabolic reprogramming.
Minghao Xu, Chenhao Zhou, Jialei Weng, Zhaoshuo Chen, Qiang Zhou, Jian Gao, Guoming Shi, Aiwu Ke, Ning Ren, Huichuan Sun, Yinghao Shen   +10 more
doaj   +1 more source

Total-liver-volume perfusion CT using 3-D image fusion to improve detection and characterization of liver metastases

, 2008
The purpose of this study was to evaluate the feasibility of a totalliver- volume perfusion CT (CTP) technique for the detection and characterization of livermetastases.
Cornelis van Kuijk, van Waesberghe, Jan, Meijer, Sybren, Weide, Lineke van der, Sybren Meijer, van Kuijk, C., van den Tol, Petrousjka, Lineke van der Weide, van den Tol, M.P., van der Weide, L., Meijer, S., van der Weide, Lineke, Meijerink, Martijn, Martijn R. Meijerink, Jan Hein T. M. van Waesberghe, Meijerink, M.R., van Waesberghe, J.H.T.M., Kuijk, Cornelis van, Petrousjka van den Tol, Waesberghe, Jan van, Tol, Petrousjka van den   +20 more
core   +1 more source

Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis [PDF]

, 2013
Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase (ILK)-PINCH-Parvin-α) complex.
Bhave, VS, Haynes, MM, Donthamsetty, Shashikiran, George K Michalopoulos, Shashikiran Donthamsetty, Meagan M Haynes, Mars, WM, Orr, A, Haynes, Meagan M., Bowen, WC, Anne Orr, Chuanyue Wu, Wu, Chuanyue, Orr, Anne, William C Bowen, Wu, C, Singh, Shree Ram, Vishakha S Bhave, Wendy M Mars, Bhave, Vishakha S., Michalopoulos, George K., Bhave, Vishakha, Donthamsetty, S, Mars, Wendy M., Michalopoulos, GK, Bowen, William C.   +25 more
core   +1 more source